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Proteomic analysis of brain structures derived from GGT subjects
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD015768 | Pride
Here we used double-transgenic amyloid precursor protein/presenilin 1 (APPswe/PS1dE9) mice and label-free quantitative proteomics to analyze potential early pathological effects on the olfactory bulb (OB) during AD progression.
ORGANISM(S): Mus musculus (Mouse) 
2016-08-09 | PXD003683 | Pride
Proteomic analysis were performed in olfactory bulbs derived from controls and individuals with dementia with lewy bodies
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD016069 | Pride
A mild olfactory dysfunction has been observed in frontotemporal dementias (FTD). However, the underlying molecular mechanisms associated to this deficit are poorly understood. Here, we applied mass spectrometry-based quantitative proteomics to analyse pathological effects on the olfactory bulb (OB)...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD011446 | Pride
Despite smell impairment has been considered a potential non-motor finding in ALS, the pathobiochemistry at olfactory level remains unknown. Here, we applied an olfactory quantitative proteotyping approach to analyze the magnitude of the olfactory bulb (OB) proteostatic imbalance in ALS subjects (n=...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021630 | Pride
Olfactory dysfunction is one of the earliest features in Lewy-type alpha-synucleinopathies (LTS) such as Parkinson´s disease (PD). However, the underlying molecular mechanisms associated to smell impairment is poorly understood. To reveal the missing links in the biochemical understanding of olfacto...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD008036 | Pride
Label-free quantitative proteomics were applied to the amygdaloid complex derived from non-demented, AD-Braak stage I-II, and AD-Braak stage III-IV subjects to study the molecular mechanisms disrupted in initial neuropathological stages
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD069452 | Pride
Olfactory dysfunction is among the earliest features of Alzheimer´s disease (AD). Although neuropathological abnormalities have been detected in the olfactory bulb (OB), little is known about its dynamic biology. Here, OB- proteome analysis was performed across different AD stages using a label-free...
ORGANISM(S): Homo sapiens (Human) 
2018-01-16 | PXD005319 | Pride
In this study, we evaluated the common proteomic profile, as well as, the exclusively deregulated proteins in ON cells from healthy controls cannabis users (HC/c), SCZ patients non-cannabis users (SCZ/nc) and SCZ patients cannabis users (SCZ/c) as compared to healthy controls non-cannabis users (HC/...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020739 | Pride
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