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In the era of open-modification search engines, more post-translational modifications than ever can be detected by LC-MS/MS-based proteomics. This development can switch proteomics research into a higher gear, as PTMs are key in many cellular pathways important in cell proliferation, migration, meta...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD043476 | Pride
Aflatoxin B1 (AFB1), a potent dietary carcinogen, and Epstein-Barr virus (EBV), an oncogenic virus, are both implicated in cancer development, particularly in endemic regions. However, the combined effects of AFB1 exposure and EBV infection on the epigenetic landscape remain poorly understood. This ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-23 | PXD060719 | Pride
Epigenetic modifications are dynamic and reversible, making them attractive targets for therapeutic intervention in cancer. Although several epigenetic drugs (epidrugs) have been clinically approved, their application in T-cell acute lymphoblastic leukemia (T-ALL) remains limited, and predictive bio...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067935 | Pride
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