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We aimed to in-depth characterize and quantify salivary N-glycoproteomics. HILIC enrichment and LC-MS/MS were combined to investigate salivary glycosylation both at deglycopeptides level and glycopepeptides level, and alterations in site-specific glycoforms for human saliva were detected between lun...
ORGANISM(S): Homo sapiens (Human) 
2023-02-08 | PXD030670 | Pride
For this project N-glycosylated peptides were extracted from tissue of a mouse model for ovarian cancer tissue and matched control mice. The extracted N-glycosites were analyzed by LC-MSMS
ORGANISM(S): Mus musculus (Mouse) 
2019-07-01 | PXD005665 | Pride
our study offers a convenient and robust site-specific chemproteomics tool for glycoproteome profiling, enabling simultaneous identification of O-GlcNAc sites and N-glycosites by a two-step enzymatic release strategy
ORGANISM(S): Homo Sapiens 
2024-01-12 | PXD048484 |
Human plasma fibronectin is an adhesive protein that plays a crucial role in wound healing. Many studies had indicated that glycans may mediate the expression and functions of fibronectin, yet a comprehensive understanding of its glycosylation is still missing. Here, we performed a comprehensive N- ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025886 | Pride
The densely glycosylated spike (S) proteins that are highly exposed on the surface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) facilitate viral attachment, entry, and membrane fusion. We have previously reported all the 22 N-glycosites and site-specific N-glycans in the S protein...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD022896 | Pride
Von Willebrand Factor (vWF), a plasma glycoprotein, plays essential roles in primary hemostasis, in cooperation with other coagulation factors. The glycosylation affects many biological phases during the protein life-cycle. In this work, we comprehensively characterized the microheterogeneity at all...
ORGANISM(S): Homo sapiens (Human) 
2022-02-23 | PXD006567 | Pride
Most patients with triple negative breast cancer (TNBC) fail to respond to anti-PD1/PDL1 immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a highly glycosylated protein. However, the mechanisms of B7H3 glycosylation regulation and whether the sugar moiety contribu...
ORGANISM(S): Homo sapiens (Human) 
2021-03-15 | PXD024672 | Pride
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