Sort   by:  
 Page size 
TranscriptomicsSodium arsenite induced gene expression changes in A549 human epithelial lung carcinoma cells
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns which could lead to altered gene expression Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 ...
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44169 | biostudies-arrayexpress
ProteomicsMolecular Disruption and Dysfunction in the Thyroid of Rats Chronically Exposed to NaAsO2-Insights Unveiled through Proteomic and Phosphoproteomic Analyses
Arsenic, ubiquitously present as a hazardous metalloid, constitutes a significant danger to human health. Although investigations into the detrimental effects of arsenic on the thyroid have been initiated by researchers, a comprehensive exploration of its toxicological impact and underlying molecula...
ORGANISM(S): Rattus Norvegicus 
PXD056135 |
TranscriptomicsSodium arsenite induced DNA methylation changes in A549 human epithelial lung carcinoma cells
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 M-BM-5M, 0.4 M-BM-5M and 2 M-BM-5M for 1, 2 ...
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44173 | biostudies-arrayexpress
ProteomicsProximity labelling with TurboID shows that client proteins of PML NBs differ in three cell contexts
PML nuclear body (PML NB) recruits different client proteins under different cell context. We used TurboID proximity labeling (PL) method followed by MS to determine the composition of PML NBs in mESCs, differentiated cells, and NaAsO2-treated mESCs.
ORGANISM(S): Mus musculus (Mouse) 
2023-01-10 | PXD037432 | Pride
Pml Differentiation Mesc Turboid Naaso2 
TranscriptomicsEffect of long-term sodium arsenite treatment on transcriptomic profiles in progenitor and differentiated HepaRG cells.
Inorganic arsenic, a ubiquitous environmental contaminant of food and drinking water, is a human carcinogen associated with lung, liver, prostate, renal, and bladder cancers. It has been postulated that inorganic arsenic targets stem cells or partially differentiated progenitor cells, causing their ...
ORGANISM(S): Homo sapiens 
2017-09-15 | GSE103873 | GEO
TranscriptomicsIntegrating phenotypic and expression profiles to map arsenic response networks
The parent S. cerevisiae strain, BY4741, and specific gene deletions of the parent S.cerevisiae strain BY4741 were treated with 100uM NaAsO2 (AsIII) for 2h and compared to the untreated counterpart (yap1Î? vs. yap1Î? 2h 100uM AsIII, cad1Î? vs. cad1Î? 2h 100uMAsIII, rpn4Î? vs. rpn4Î? 2h 100uM AsIII, ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-05 | E-GEOD-1798 | biostudies-arrayexpress
MetabolomicsArsenic induces metabolome remodeling in mature human adipocytes
Human lifetime exposure to arsenic through drinking water, food supply or industrial pollution leads to its accumulation in many organs such as liver, kidneys, lungs or pancreas but also adipose tissue. Recently, population-based studies revealed the association between arsenic exposure and the deve...
2025-05-23 | MTBLS8808 | MetaboLights
TranscriptomicsTranscriptomic analysis in Caenorhabditis elegans exposed to organic and inorganic forms of arsenic or mercury
Arsenic and mercury are known chemical hazards. The differences in effects from organic and inorganic forms of these toxic elements is less well understood, however. The nematode Caenorhabditis elegans (C. elegans) is a suitable model to investigate the toxicity of environmental hazards. In this stu...
ORGANISM(S): Caenorhabditis elegans 
2022-02-18 | GSE196891 | GEO
UnknownEffect of PINK1 and Parkin gene silencing on sodium arsenite-induced mitophagy in normal rat liver cells (BRL-3A).
Not available
S-EPMC8882795 | biostudies-literature
UnknownEffect of Sodium Arsenite on the Expression of Antioxidant Genes (SOD2 and CAT) in MCF-7 and Jurkat Cell Lines.
Not available
S-EPMC5402782 | biostudies-literature
Sort   by:  
 Page size