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ProteomicsCerebral organoids proteomics - Human Cerebral Organoids and Fetal Brain Tissue Share Proteomic Similarities
Pluripotent stem cells (PSC) can differentiate inot any cell type of an organism. Their remarkable capability of self-organization enables the formation of three-dimensional structures that resembles miniature organs, including cerebral organoids. These organoids can recreate early steps of the hum...
ORGANISM(S): Homo sapiens (Human) 
2019-11-15 | PXD011605 | Pride
Pluripotent stem cell Progenitors Cerebral organoids Neural Minibrain 
ProteomicsProteomic signatures of schizophrenia-sourced iPSC-derived neural progenitors and neurons
Schizophrenia is a complex and severe neuropsychiatric disorder, with a wide range of debilitating symptoms. Several aspects of its multifactorial complexity are still unknown, and some are accepted to be an early developmental deficiency with a more specifically neurodevelopmental origin. Understan...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026593 | Pride
Neuron Scz Neural cell Disease Hnpc Organoid Ips Proteome 
ProteomicsProteomic signatures of schizophrenia-sourced iPSC-derived brain organoids
Schizophrenia is a complex and severe neuropsychiatric disorder, with a wide range of debilitating symptoms. Several aspects of its multifactorial complexity are still unknown, and some are accepted to be an early developmental deficiency with a more specifically neurodevelopmental origin. Understan...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026381 | Pride
Neuron Cerebral organoid Scz Neural cell Disease Hnpc Ips Proteome 
ProteomicsProteomic signatures of schizophrenia-sourced iPSC-derived astrocytes
Schizophrenia is a complex and severe neuropsychiatric disorder, with a wide range of debilitating symptoms. Several aspects of its multifactorial complexity are still unknown, and some are accepted to be an early developmental deficiency with a more specifically neurodevelopmental origin. ??Molecul...
ORGANISM(S): Homo sapiens (Human) 
2023-04-27 | PXD031640 | Pride
Scz Glial cells Strocyte Disease Hipsc Proteome 
ProteomicsTNF-alpha stimulated secretome of schizophrenia-sourced iPSC-derived astrocytes
Schizophrenia is a complex and severe neuropsychiatric disorder, with a wide range of debilitating symptoms. Several aspects of its multifactorial complexity are still unknown, and some are accepted to be an early developmental deficiency with a more specifically neurodevelopmental origin. ??Molecul...
ORGANISM(S): Homo sapiens (Human) 
2023-04-27 | PXD031650 | Pride
Scz Glial cells Disease Hipsc Astrocyte Proteome Conditioned media 
ProteomicsProteomic changes of ZIKV and DENV in iPS-derived neurospheres
Brain abnormalities and congenital malformations have been linked to the circulating strain of Zika virus (ZIKV) in Brazil since 2016 during the microcephaly outbreak; however, the molecular mechanisms behind several of these alterations and differential viral molecular targets have not been fully e...
ORGANISM(S): Homo sapiens (Human) 
2022-06-29 | PXD026909 | Pride
Microcephaly Nsc Neurodevelopment Ipsc Dengue Flaviviridae Zika 
ProteomicsProteomic changes of ZIKV strains and DENV in neural stem cells
Brain abnormalities and congenital malformations have been linked to the circulating strain of Zika virus (ZIKV) in Brazil since 2016 during the microcephaly outbreak; however, the molecular mechanisms behind several of these alterations and differential viral molecular targets have not been fully e...
ORGANISM(S): Homo sapiens (Human) 
2022-06-29 | PXD026825 | Pride
Microcephaly Nsc Neurodevelopment Ipsc Dengue Flaviviridae Zika 
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