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ProteomicsSurveying the vampire bat (Desmodus rotundus) serum proteome: a resource for identifying immunological proteins and detecting pathogens
Bats are increasingly studied as model systems for longevity and as natural hosts to some virulent viruses. Yet our ability to characterize immune mechanisms of viral tolerance and to quantify infection dynamics in wild bats is often limited by small sample volumes and few species-specific reagents....
ORGANISM(S): Desmodus rotundus 
2020-12-07 | PXD022885 | Pride
Lc-msms Dia Vampire bat Serum 
ProteomicsIdentifcation of Adiponectin and Evidence for Post-Translational Modifications in the Bottlenose Dolphin (Tursiops truncatus)
A Multiple Affinity Removal System (MARS) Human 14 spin cartridge was used to deplete a dolphin serum which was then digested with trypsin and analyzed without prior fractionation by nanoLC-MS/MS. These files are associated with "2011-9-25_Neely-DolphinSerum." Data analysis: raw data generated by th...
ORGANISM(S): Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) 
2013-09-23 | PXD000431 | Pride
Adiponectin Ptms Dolphin Tursiops truncatus 
ProteomicsProteomic analysis of California sea lion urine
It is often necessary to demonstrate measurement capabilities in fields not already using state of the art bioanalytical platforms in order to encourage metrological modernization and adoption of such technologies. Marine mammal proteomics is a burgeoning field with diverse stakeholders and rapid in...
ORGANISM(S): Zalophus californianus (California sealion) 
2018-06-06 | PXD009019 | Pride
Marine mammal Urine California sea lion 
ProteomicsProteomic analysis of six different tissues from the Atlantic bottlenose dolphin (Tursiops truncatus)
Proteomic analysis of six tissues (liver, kidney, blubber, brain, muscle, skin) provided experimental confirmation of 10,402 proteins from 4,711 protein groups, almost 1/3 of the possible predicted proteins in the Atlantic bottlenose dolphin (Tursiops truncatus) NCBI annotation (release 101), which ...
ORGANISM(S): Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) 
2018-02-09 | PXD008808 | Pride
Brain Skin Liver Kidney Atlantic bottlenose dolphin Blubber Tursiops truncatus Muscle 
ProteomicsIdentification of candidate protein biomarkers associated with domoic acid toxicosis in cerebrospinal fluid of California sea lions (Zalophus californianus)
Since 1998, California sea lion stranding events associated with domoic acid toxicosis (DAT) have consistently increased and there are no practical non-lethal clinical tests for the diagnosis of domoic acid toxicosis that can be utilized in a large-scale rehabilitation facility. Proteomic analysis w...
ORGANISM(S): Zalophus californianus (California sealion) 
2023-04-05 | PXD041356 | Pride
Cerebrospinal fluid Lc-msms California sea lion Domoic acid toxicosis 
ProteomicsIdentifying candidate markers of domoic acid toxicosis in undepleted plasma from California sea lions (Zalophus californianus)
This data is a re-analysis of samples used in a prior study (doi:10.1371/journal.pone.0123295) evaluating plasma candidate biomarkers of chronic domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus). The previous study used 2D-gel electrophoresis to analyze plasma from a train...
ORGANISM(S): Zalophus californianus (California sealion) 
2020-07-17 | PXD020366 | Pride
Domoic acid Lc-msms California sea lion Plasma 
ProteomicsCalifornia sea lion cerebrospinal fluid LC-MS/MS
We conducted a pilot label-free LC-MS/MS study to profile and compare the cerebral spinal fluid from California sea lions with domoic acid toxicosis and without domoic acid toxicosis. CSF samples from a 8 animals with DAT and 3 controls were run on a nano LC-MS/MS (Triple TOF) and searched against a...
ORGANISM(S): Zalophus californianus (California sealion) 
2015-09-21 | PXD002105 | Pride
Cerebrospinal fluid Domoic acid California sea lion 
ProteomicsCalifornia sea lion plasma chronic DAT biomarkers via 2D-GE
Domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus) is caused by exposure to the marine biotoxin domoic acid and has been linked to massive stranding events and mortality. Diagnosis is based on clinical signs in addition to the presence of domoic acid in body fluids. Chronic...
ORGANISM(S): Zalophus californianus (California sealion) 
2015-04-30 | PXD001606 | Pride
2d-ge Sea lion Plasma Depletion Apoe 
ProteomicsProteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue
We analyzed 84 tumor/normal pairs (177 total) using standard shotgun proteomic techniques in order to characterize the molecular landscape of clear cell renal cell carcinoma (ccRCC) and interrogated changes in protein abundance and biological pathways with ccRCC grade. These tissues were distributed...
ORGANISM(S): Homo sapiens (Human) 
2016-04-18 | PXD003271 | Pride
Tissue Renal cell carcinoma Kidney Human Ccrcc Lc-ms/ms 
ProteomicsProteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue
We analyzed 84 tumor/normal pairs (177 total) using standard shotgun proteomic techniques in order to characterize the molecular landscape of clear cell renal cell carcinoma (ccRCC) and interrogated changes in protein abundance and biological pathways with ccRCC grade. These tissues were distributed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079972 | MassIVE
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