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TranscriptomicsTranscription profiling of Bacillus subtilis treated with plectasin
transriptional profiling of Bacillus subtilis treated with Plectasin
ORGANISM(S): Bacillus subtilis strain 168 
2009-10-20 | E-MTAB-60 | biostudies-arrayexpress
ProteomicsMajor Proteomic Changes Associated with Amyloid Induced Biofilm Formation in Pseudomonas aeruginosa PAO1
The newly identified functional amyloids in Pseudomonas (Fap) are associated with increased aggregation and biofilm formation in the opportunistic pathogen P. aeruginosa. However, whether this phenomenon can be simply ascribed to the mechanical properties of the amyloid fibrils remains...
ORGANISM(S): Pseudomonas Aeruginosa Pao1 (ncbitaxon:208964) 
MSV000082917 | MassIVE
ProteomicsData in support of Identification of brain antigens recognized by autoantibodies in experimental autoimmune encephalomyelitis-induced animals treated with Etomoxir or Interferon-beta
Multiple Sclerosis is a neurogenerative disease, where inflammation plays an essential role and the loss of tolerance for self produces proteins is a key feature. To investigate the autoimmune response, we use serum from experimental autoimmune encephalomyelitis (EAE) induced rats and investigate au...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-05-14 | PXD008835 | Pride
Multiple sclerosis Autoantibodies Experimental autoimmune encephalomyelitis Rat model Inflammation Autoantigens Etomoxir 
ProteomicsData in support of Identification of potential autoantigens in anti-CCP-positive and anti-CCP-negative rheumatoid arthritis
The presence or absence of autoantibodies against citrullinated proteins (ACPAs) distinguishes two main groups of rheumatoid arthritis (RA) patients with different etiology, prognosis, disease severity, and, presumably, disease pathogenesis. The heterogeneous responses of RA patients to various biol...
ORGANISM(S): Homo sapiens (Human) 
2022-01-05 | PXD024955 | Pride
Proteomics Autoantibodies Citrullination Rheumatoid arthritis Autoimmune 
ProteomicsData in support of Gold micro-particles for knee osteoarthritisGold micro-particles for knee osteoarthritis
This study investigated the effect of intraarticular gold micro particle implants for the treatment of pain and inflammation in KOA. The present open, exploratory, proof-of-concept study investigated whether intraarticular gold ions could act as a KOA treatment option through modulation of inflammat...
ORGANISM(S): Homo sapiens (Human) 
2022-12-03 | PXD030746 | Pride
Osteoartritits Pain Proteomics Gold Inflammation 
MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
TranscriptomicsDifferential regulation of microRNAs in skeletal muscle from monozygotic twins discordant for type 2 diabetes
Analysis of microRNA expression in vastus lateralis muscle biopsies from 11 genetically identical twin pairs discordant for type 2 diabetes. This eliminates the influence of genotype and leads to the identification of microRNAs that are exclusively influenced by environmental (non-genetic) factors. ...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-38835 | biostudies-arrayexpress
UnknownBiotic interactions are an unexpected yet critical control on the complexity of an abiotically driven polar ecosystem.
Not available
S-EPMC6377621 | biostudies-literature
TranscriptomicsGenome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes
Monozygotic twins discordant for type 2 diabetes constitute an ideal model to study environmental contributions to type 2 diabetic traits. We aimed to examine whether global DNA methylation differences exist in major glucose metabolic tissues from twelve 53–80 year-old monozygotic discordant twin pa...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-38291 | biostudies-arrayexpress
UnknownCardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis.
Not available
S-EPMC4648058 | biostudies-literature
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