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MetabolomicsA Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease
Identification of chronic kidney disease patients at risk of progressing to end-stage renal disease (ESRD) is essential for treatment decision-making and clinical trial design. Here, we explored whether proton nuclear magnetic resonance (NMR) spectroscopy of blood plasma improves the currently best ...
2019-07-26 | MTBLS798 | MetaboLights
MetabolomicsUrine Latin Square Spike-In for testing the NMR quantification tool, MetaboQuant
To test the quantification performance of MetaboQuant and other NMR quantification tools, a set of eight metabolites were added to replicates of a urine sample in varying concentrations. The metabolites were alanine, creatinine, histidine, betaine, acetate, phosphocreatine, β-hydroxybutyrate (BHBA) ...
2013-01-10 | MTBLS25 | MetaboLights
ProteomicsProteomics of Small Extracellular Vesicles from Melanoma DCC-Derived Cell Lines
Small extracellular vesicles (sEVs) were isolated from the culture supernatant of melanoma DCC-derived cell lines (MelDCC) after 48 hours of serum-free culture. sEVs were obtained through differential ultracentrifugation, specifically as the 100K pellet, following the protocol described in detail by...
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD059510 | Pride
Lc-ms/ms Melanoma Extracellular vesicles 
ProteomicsBottom-up proteomics of FFPE tissue section from DLBCL patients
FFPE tissue sections of lymphoma patients were analyzed. All patients were enrolled in prospective multicenter DSHNHL clinical trials. The study included DLBCL samples from 357 patients.
ORGANISM(S): Homo sapiens (Human) 
2025-09-06 | PXD058736 | Pride
Lymphoma Micro hplc-ms/ms 
MetabolomicsRare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism

We investigated the cumulative contribution of rare, exonic genetic variants on the concentration of 1,487 metabolites and 53,714 metabolite ratios in urine by performing gene-based tests based on 226,233 variants from up to 4,864 participants of the German Chronic Kidney Disease (GCKD)...

2021-03-09 | MTBLS284 | MetaboLights
ProteomicsPlatform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue
10 µm formalin-fixed paraffin-embedded tissue sections were deparaffinized with xylene; homogenization was performed in lysis-buffer (20 mM Tris-HCl, pH 8.8, 200 mM glycine, 200 mM DTT, 4% SDS)in an ultrasonic bath; samples were incubated under continuous agitation first at 99 °C for 30 min, then a...
ORGANISM(S): Homo sapiens (Human) 
2020-05-18 | PXD012317 | Pride
Lymphoma Dlbcl Proteomics Swath-ms Cell of origin 
ProteomicsComprehensive metaboproteomics of Burkitt’s and diffuse large B-cell lymphoma cell lines and primary tumor tissues
Comparative proteome analysis of BL and DLBCL cell lines, cryopreserved and formalin-fixed paraffin-embedded (FFPE) primary tumor specimens by SWATH-MS.
ORGANISM(S): Homo sapiens (Human) 
2017-02-08 | PXD004936 | Pride
Ffpe Bl Cell lines Swath-ms Cryopreserved Dlbcl 
ProteomicsHodgkin lymphoma-educated macrophages
Comparative proteome analysis of HL and DLBCL educated human macrophages by SWATH-MS.
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD016128 | Pride
Lymphoma Swath Macrophages Cd206 
UnknownMetaboSERV-a platform for selecting, exchanging, and visualizing metabolomics data with controlled data access.
Not available
S-EPMC12315529 | biostudies-literature
UnknownSpatial Cellular Networks from omics data with SpaCeNet.
Not available
S-EPMC11529864 | biostudies-literature
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