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ProteomicsPhosphoproteomic analysis of brain form Alzheimer’s disease
Alzheimer's disease (AD), the most common neurodegenerative disorder caused by neuronal loss which results in memory loss. Formation of neurofibrillary tangles composed of abnormal hyper phosphorylation of tau protein is one of the major pathological hallmarks for AD. Several neurodegenerative disor...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD010807 | Pride
Tmt Alzheimer's disease (ad) Phosphoproteome 
ProteomicsA draft map of the human proteome
The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides does not exist yet. Here, we report a draft map of the human proteome based on high resolution Fouri...
ORGANISM(S): Homo sapiens (Human) 
2014-04-24 | PXD000561 | Pride
Proteogenomics Human proteome map Lc-ms/ms 
ProteomicsReanalysis of Pandey lab's draft of the human proteome
The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides was lacking. To this end, Akhilesh Pandey's lab reported a draft map of the human proteome based on...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-PROT-1 | biostudies-arrayexpress
ProteomicsGlycoproteomic and proteomic alterations in SRD5A3-deficient fibroblasts
SRD5A3-CDG is a congenital disorder of glycosylation (CDG) resulting from pathogenic variants in SRD5A3 and follows an autosomal recessive inheritance pattern. The enzyme encoded by SRD5A3, polyprenal reductase, plays a crucial role in synthesizing lipid precursors essential for N-linked glycosylati...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055397 | Pride
Dolichol Lipid-linked oligosaccharide Cdg type i N-glycosylation Polyprenol 
ProteomicsBIOSITe: A novel method for direct detection of site specific biotinylation
Proximity-dependent biotinylation methods, such as those mediated by BioID and APEX, are being widely adopted for studying in vivo protein-protein interaction dynamics and subcellular structures. However, these along with other biotin-based technologies are severely dependent on avidin family protei...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-12-19 | PXD007862 | Pride
Bioid Proximity dependent biotinylation Bcr abl Mass spectrometry Ip Peptide Biotinylation Biosite 
ProteomicsA proteomic map of the human aqueous humor
The aqueous humor is a colourless, transparent fluid that fills the anterior chamber of the eye. It has an important role to play in maintaining the intraocular pressure of the eye and providing nourishment to avascular structures such as the lens and cornea. It is also essential for providing a cle...
ORGANISM(S): Homo sapiens (Human) 
2016-01-04 | PXD000787 | Pride
Human Brplc Aqueous humor Trypsin Scx Humor Ingel Eye Lc-ms/ms 
ProteomicsA proteomic map of the human aqueous humor
The aqueous humor is a colourless, transparent fluid that fills the anterior chamber of the eye. It has an important role to play in maintaining the intraocular pressure of the eye and providing nourishment to avascular structures such as the lens and cornea. It is also essential for providing a cle...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081764 | MassIVE
ProteomicsMacrophage migration inhibitory factor - a therapeutic target in gallbladder cancer
Poor prognosis in gallbladder cancer is due to late presentation of the disease, lack of reliable biomarkers for early diagnosis and limited targeted therapies. Early diagnostic markers and novel therapeutic targets can significantly improve clinical management of GBC. We carried out quantitative pr...
ORGANISM(S): Homo sapiens (Human) 
2015-10-02 | PXD001566 | Pride
Quantitative proteomics Targeted therapy Rna interference Gastrointestinal cancer Suicide substrate Bottom-up proteomics 
ProteomicsDYRK1A, a potential therapeutic target for head and neck squamous cell carcinoma
To identify the activated tyrosine kinase signaling pathways in HNSCC, we carried out phosphotyrosine profiling using a panel of HNSCC cell lines compared to a normal oral keratinocyte. A total of 61 unique phosphosites were identified across these cell lines. Dual-specificity tyrosine-(Y)-phosphor...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002132 | Pride
Dual specificity kinases Head and neck squamous cell carcinoma Phosphoproteomics 
Proteomics,MultiomicsA draft map of the human proteome
The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides does not exist yet. Here, we report a draft map of the human proteome based on high resolution Fouri...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-02-16 | MSV000079514 | MassIVE
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