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TranscriptomicsTranscription profiling of human basal-like breast cancer - in vitro and in vivo Analysis of B-Myb
The basal-like breast cancer subtype portends a poor clinical prognosis, and a defining feature of this subtype is the high expression of genes in the “proliferation signature”. B-Myb, a member of the MYB protein family of transcription factors, is highly expressed in the proliferation signatur...
ORGANISM(S): Homo sapiens 
2009-01-18 | E-GEOD-11429 | biostudies-arrayexpress
ProteomicsSurface proteomics reveals CD72 as a target for in vitro-evolved nanobody-based CAR-T cells in refractory B-cell malignancies
Alternate strategies are needed for B-cell malignancy patients relapsing after CD19-targeted immunotherapy. Here, integrated cell surface proteomics and epigenetic analysis initially revealed CD72 as an optimal target for poor-prognosis MLL-rearranged B-ALL, which we further found to be expressed wi...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD016800 | Pride
B-all Cell surface Cd72 
TranscriptomicsComparative Genomic Analysis of Clinical Strains of Campylobacter jejuni from South Africa
Background. The bacterial foodborne pathogen Campylobacter jejuni is a common cause of acute gastroenteritis and is also associated with the postinfectious neuropathies, Guillain-Barré and Miller Fisher syndromes. This study described the use of multilocus sequence typing and DNA microarrays to e...
ORGANISM(S): Campylobacter jejuni 
2010-05-27 | E-GEOD-9862 | biostudies-arrayexpress
ProteomicsAltered Subgenomic RNA Abundance in SARS-CoV-2 B.1.1.7 Infections
SARS-CoV-2 lineage B.1.1.7 viruses are more transmissible, may lead to greater clinical severity, and result in modest reductions in antibody neutralization. Subgenomic RNA(sgRNA) is produced by discontinuous transcription of the SARS-CoV-2 genome. Applying our tool(periscope) to ARTIC Network Nanop...
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2021-11-26 | PXD029954 | Pride
Sars-cov-2 B.1.1.7 Coronavirus 
TranscriptomicsAn oncogenic Ezh2 mutation cooperates with particular genetic alterations to induce tumors in mice and redistributes H3K27m3 through the genome [RNA-seq]
B-cell lymphoma and melanoma harbor recurrent mutations in the gene encoding the EZH2 histone methyltransferase, but the carcinogenic role of these mutations is unclear. Here we describe a mouse model in which the most common somatic EZH2 gain-of-function mutation (Y646F in human, Y641F in the mous...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-79035 | biostudies-arrayexpress
GenomicsLeft ventricular systolic dysfunction in female NBCe1-B/C-knockout mice
Left ventricular systolic dysfunction in female NBCe1-B/C-knockout mice
PRJNA925818 | ENA
TranscriptomicsGenomic characterization implicates iAMP21 as a primary genetic event in childhood B-cell precursor acute lymphoblastic leukaemia
Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct subgroup of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) shown to have a dismal outcome on standard therapy. For improved diagnosis and prognosis of these patients, the initiating genetic events need to ...
ORGANISM(S): Homo sapiens 
2012-03-02 | E-GEOD-26192 | biostudies-arrayexpress
ProteomicsIdentification of neoantigens in oesophageal adenocarcinoma
We present data from tissues of seven oesophageal adenocarcinomas of CD4 and CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound peptides.This dataset forms part of the publication:Nicholas, B., Bailey, A., McCann, K.J., Wood, O., Walke...
ORGANISM(S): Homo sapiens (Human) 
2022-09-27 | PXD031108 | Pride
Human Oesophageal adenocarcinoma Immunopeptidome Hla 
UnknownParker Solar Probe Imaging of the Night Side of Venus.
Not available
S-EPMC9286398 | biostudies-literature
ProteomicsZebrafish caudal fin phosphoproteomic of Rps6kb1a/b knockdown
Knocked-down of P70S6K in zebrafish (double knockdown of rps6kb1/2) using embryo Cas9/gRNA RNP injections followed by phosphoproteomics of caudal fin.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-12-16 | PXD054212 | Pride
Phosphoproteomics P70s6k Rps6kb1 Zebrafish 
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