Sort   by:  
 Page size 
ProteomicsRNF10 and RIOK3 Facilitate 40S Ribosomal Subunit Degradation upon 60S Biogenesis Disruption or Amino Acid Starvation [Fig. 5B, S5C-E]
Ribosome-associated quality control (RQC) pathways target ribosomes whose progression becomes impaired during various phases of the translation cycle. Ribosome ubiquitylation is a key RQC licensing step. Previous studies identified an initiation specific RQC branch (iRQC) that is activated when tran...
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060206 | Pride
Riok3 Ribosome ubiquitylation Initiation ribosome-associated quality control (irqc) Amino acid starvation Rnf10 Ribosome biogenesis 
UnknownNatural mucosal barriers and COVID-19 in children.
Not available
S-EPMC8262299 | biostudies-literature
TranscriptomicsComparative Analysis of RNA-Seq Alignment Algorithms and the RNA-Seq Unified Mapper (RUM).
A critical task in high throughput sequencing is aligning millions of short reads to a reference genome. Alignment is especially complicated for RNA sequencing (RNA-Seq) because of RNA splicing. A number of RNA-Seq algorithms are available, and claim to align reads with high accuracy and efficiency ...
ORGANISM(S): Mus musculus 
2011-08-03 | E-GEOD-26248 | biostudies-arrayexpress
ProteomicsRickettsia raoultii intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia raoultii Xenopus laevis (African clawed frog) 
2018-10-25 | PXD003193 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsRickettsia conorii intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia conorii (strain ATCC VR-613 / Malish 7) 
2018-10-25 | PXD003194 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsRickettsia massiliae intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia massiliae (strain Mtu5) Xenopus laevis (African clawed frog) 
2018-10-25 | PXD003197 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsRickettsia slovaca intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia slovaca (strain 13-B) 
2018-10-25 | PXD003195 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsNeuronal aging leads to disrupted RNA metabolism
Aging is one of the most prominent risk factors for neurodegeneration, yet the molecular mechanisms underlying the deterioration of old neurons are mostly unknown. To efficiently study neurodegeneration in the context of aging, we transdifferentiated primary human fibroblasts from aged (i.e. >50 yea...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD055826 | Pride
Human Neuron Transdifferentiation 
MetabolomicsAn Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors
Direct infusion high-resolution mass spectrometry (DIHRMS) is a novel, high-throughput approach to rapidly and accurately profile hundreds of lipids in human serum without prior chromatography, facilitating in-depth lipid phenotyping for large epidemiological studies to reveal the detailed associati...
2024-02-02 | MTBLS4461 | MetaboLights
ProteomicsA U1-70K Protein Interaction Network Reveals a Functional Class of RNA Binding Proteins with Mixed Charge Domains
U1 small nuclear ribonucleoprotein 70 kDa (U1-70K) and other proteins of the spliceosome complex are mislocalized to cytoplasmic aggregates in Alzheimer’s disease (AD) brain, yet understanding of the specific mechanisms that cause their aggregation is limited. Many of the RNA binding proteins (RBPs)...
ORGANISM(S): Homo sapiens (Human) 
2018-06-21 | PXD008260 | Pride
U1-70k 
Sort   by:  
 Page size