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Histone proteomics from 5 human cell lines, discussed in publication: "A practical guide for analysis of histone post-translational modifications by mass spectrometry: best practices and pitfalls". Further explanation of data types, methods, and analysis are available in Data Explanation document in...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
Frontotemporal dementias are neuropathologically characterized by frontotemporal lobar degeneration (FTLD). Intraneuronal inclusions of transactive response DNA-binding protein 43 kDa (TDP-43) are the defining pathologic hallmark of approximately half of the FTLD cases, being referred to as FTLD-TDP...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-12 | MSV000089242 | MassIVE
This dataset consists of 4 raw MS files and associated peak lists and results files, acquired on a Bruker timsTOF Pro 2 operated in Data Dependent Acquisition mode. Samples were generated by Tiffany Cho. Affinity purification was performed by Tiffany Cho and Laura McGary. Mass spectrometry acquisit...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-03-05 | MSV000094236 | MassIVE
This experiment investigated transcriptomic responses of mouse intestinal adenoma organoids to circulating factors induced by acute exercise. Intestinal adenoma organoids derived from an Lgr5-creER;Apcfl/fl mouse model were cultured with 1% human serum collected immediately before or after a maximal...
ORGANISM(S): Mus musculus 
In the project “Phosphoproteomic analysis of UBQLN2 mutant cells” by Laura Strohm, Zehan Hu, Jörn Dengjel, and Christian Behrends eight sets of SILAC experiments were performed, two times four biological replicates, comparing proteome and phosphoproteome of control and UBQLN2 mutant, patient-derived...
ORGANISM(S): Homo sapiens (Human) 
2022-06-28 | PXD029730 | Pride
Epigenetic modifications are dynamic and reversible, making them attractive targets for therapeutic intervention in cancer. Although several epigenetic drugs (epidrugs) have been clinically approved, their application in T-cell acute lymphoblastic leukemia (T-ALL) remains limited, and predictive bio...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067935 | Pride
This study aims to determine the global gene expression in vancomycin resistant Enterococcus faecium (VRE) in response to a novel essential oil-vancomycin combination, and the individual components (vancomycin, carvacrol and cuminaldehyde) to help determine the mechanism of action of this antimicrob...
ORGANISM(S): Enterococcus faecium 
The cornea is the transparent tissue on the anterior surface of the eye. It is notably composed of a squamous stratified epithelium that forms a barrier protecting the ocular chamber. As the cornea is avascular, the delivery of nutrients and growth factors, required for corneal physiology, is essent...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD061492 | Pride
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