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TranscriptomicsIn vivo proximity labeling and sequencing (IPL-seq) for SNRPN70 in 293T-Rex
This proof-of-principle experiment was designed to demonstrate the feasibility of proximity labeling for RNAM-bM-^@M-^Sprotein interactions IPL-seq on 293T-Rex expressing MSA-SNRPN70 (sample) or NFH-SNRPN70 (control)
ORGANISM(S): Homo sapiens 
2014-10-24 | E-GEOD-55370 | biostudies-arrayexpress
GenomicsProximity of oligodendrocytes remodels astrocytes' transcriptome
Proximity of oligodendrocytes remodels astrocytes' transcriptome
PRJNA429458 | ENA
ProteomicsSpatiotemporal Profiling of Cytosolic Signaling Complexes in Living Cells by Highly Selective Proximity Proteomics
APEX2-mediated proximity labeling pioneers in situ capture of spatiotemporal protein complexes in living cells but is limited by its high background. Here, we developed an optimized probe BP5 with much lower labeling noise. Combining the new proximity labeling with label-free quantitative proteomics...
ORGANISM(S): Homo sapiens (Human) 
2020-11-18 | PXD020709 | Pride
Protein complex Proximity labeling Spatiotemporal Proteomics 
UnknownUsing the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis.
Not available
S-EPMC6667744 | biostudies-literature
UnknownImproved intensity-based label-free quantification via proximity-based intensity normalization (PIN).
Not available
S-EPMC3993879 | biostudies-literature
ProteomicsProximity Labeling and Genetic Screening Reveals the Role of DSG2/Siglec-9 Axis in Suppressing Macrophage Phagocytosis
In current study, we have established a combined strategy using proximity labeling and genetic screening to identify the cellular ligands of Siglec-9. Our use of proximity labeling using APEX2 fusion proteins followed by quantitative proteomics allowed us to efficiently label and enrich cell surface...
ORGANISM(S): Homo sapiens (Human) 
2024-12-23 | PXD051557 | Pride
Siglec-9 Apex2 Dsg2 Proximity label 
ProteomicsHuman endosomal proximity proteome
Here, using comparative proximity proteomics of critical retrieval sub-domain components Retromer and Retriever, their cargo adaptors, and a component of the opposing ESCRT-degradative sub-domain, we provide a data-rich resource that identifies new molecular details of retrieval sub-domain compositi...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD061918 | Pride
Hela Proximity proteomics Endosomes Tmt label Lc-ms/ms 
ProteomicsRapid proximity biotinylation of the Plasmodium falciparum exported protein, SBP1
The deadly human malaria-causing parasite, Plasmodium falciparum relies on its capacity to completely remodel its host red blood cell (RBC) through the export of several hundred parasite proteins across several membranes to the RBC.We fused the exported membrane protein, skeleton binding protein 1 (...
ORGANISM(S): Plasmodium Falciparum Nf54 (ncbitaxon:5843) 
2022-06-27 | MSV000089743 | MassIVE
ProteomicsProximity labeling of FAMA transcription factor complexes in seedlings of Arabidopsis thaliana using TurboID
Identifying specific protein interactors and spatially or temporally restricted local proteomes contributes significantly to our understanding of cellular processes in virtually all aspects of life. Obtaining such data is challenging, especially when the protein, cell type or event of interest is ra...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-09-25 | PXD015161 | Pride
Seedling Plant Arabidopsis thaliana Bhlh transcription factor Stomatal guard cell Turboid Streptavidin affinity purification Proximity labeling Protein complex Fama Lc-ms/ms 
ProteomicsTurboID proximity labelling with protein TRIM52: Identification of biotinylated proteins through pull-down and label-free quantification
All constructs were expressed in RKO cells (human rectal carcinoma cell line). A fusion construct of TurboID (mutated BirA* from E. Coli) and green fluorescent protein (GFP) or human TRIM52. Cells were stimulated with Epoxomicin (proteasome inhibitor) or left untreated. Biotinylated proteins were e...
ORGANISM(S): Homo sapiens (Human) 
2025-03-25 | PXD051272 | Pride
Trim52 Proximity labelling Turboid 
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