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ProteomicsHLA-C*05:01 and HLA-C*07:02 from 721.221 cells
HLA-C expresion varies widely across the different HLA-C alleles. MicroRNA binding can partly explain the differences in HLA-C allele expression however other contributing factors still remain undetermined. Here we use two common HLA-C alleles, HLA-C*05:01 and HLA-C*07:02, to explore differences in ...
ORGANISM(S): Homo sapiens (Human) 
2017-07-03 | PXD006455 | Pride
Human Hla-c Hla class i 
ProteomicsHLA DR1 and DR15 ligands isolated from transgenic mice
Dominant protection from HLA-associated autoimmune disease is conferred by antigen specific regulatory T cells. Susceptibility and protection against human T cell mediated autoimmune diseases, including type I diabetes, multiple sclerosis and Goodpasture’s disease, is associated with particular Huma...
ORGANISM(S): Mus musculus (Mouse) 
2017-05-04 | PXD005935 | Pride
Mouse Dr15 Goodpasture’s disease Dr1 Hla class ii 
ProteomicsThe RNA-binding proteins SRP14 and HMGB3 control HIV-1 Tat mRNA processing and translation during HIV-1 latency
HIV-1 Tat protein is essential for virus production. RNA-binding proteins that facilitate Tat production may be absent or downregulated in resting CD4+ T-cells, the main reservoir of latent HIV. In this study, we examined the role of Tat RNA-binding proteins on the expression of Tat and control of l...
ORGANISM(S): Homo sapiens (Human) 
2021-06-14 | PXD025782 | Pride
Rna binding Hiv Tat Rbp 
ProteomicsHLA-DQ8 Immunopeptidomics, Type 1 Diabetes
In this project we will investigate the peptides present by HLA-DQ8. We will identify linear, spliced and PTM peptides from one cell line.
ORGANISM(S): Homo sapiens (Human) 
2021-07-07 | PXD019466 | Pride
Immunopeptidomics Type 1 diabetes Spliced 
ProteomicsImmunopeptidome of an acute myeloid leukemia cell line THP1
We report the use of complementary peptide antigen enrichment and comprehensive mass spectrometric acquisition strategies to provide in-depth immunopeptidome data for AML cell line THP1
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-07-09 | MSV000087786 | MassIVE
ProteomicsC1R.B*57:03 MHC class I immunopeptidome LC-MSMS
Characterisation of peptide ligands of Major histocompatibility class (MHC) I isolated by immunoaffinity purification from the C1R (Class I reduced) B-lymphoblastoid cell line, transfected with the MHC class I allele HLA-B*57:03.
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD008571 | Pride
Lc-msms Hla-b*57:03 Mhc Immunopeptidome 
ProteomicsC1R.B*57:01 MHC class I immunopeptidome LC-MSMS
Characterisation of peptide ligands of Major histocompatibility class (MHC) I isolated by immunoaffinity purification from the C1R (Class I reduced) B-lymphoblastoid cell line, transfected with the MHC class I allele HLA-B*57:01.
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD008570 | Pride
Lc-msms Hla-b*57:01 Mhc Immunopeptidome 
ProteomicsC1R.B*58:01 MHC class I immunopeptidome LC-MSMS
Characterisation of peptide ligands of Major histocompatibility class (MHC) I isolated by immunoaffinity purification from the C1R (Class I reduced) B-lymphoblastoid cell line, transfected with the MHC class I allele HLA-B*58:01.
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD008572 | Pride
Hla-b*58:01 Lc-msms Mhc Immunopeptidome 
ProteomicsImpacts of HLA-B57 micropolymorphism (MRM)
Comparison of peptide ligands of major histocompatibility class (MHC) I isolated by immunoaffinity purification from the C1R (Class I reduced) B-lymphoblastoid cell line, transfected with the MHC class I alleles HLA-B*57:01, HLA-B*57:03 and HLA-B*58:01.
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD009850 | Pride
Mhc Mrm Immunopeptidome Hla-b57 
ProteomicsEvidence of focusing the MHC class I immunopeptidome by tapasin
Investigation of the repertoire of peptide ligands of highly similar Major Histocompatibility complex (MHC) class I allomorphs differing in tapasin dependence; HLA-B*44:02 (tapasin dependent), HLA-B*44:05 (tapasin independent) and HLA-B*44:05 W147A mutant (tapasin dependent).
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD054743 | Pride
Hla Tapasin Immunopeptidomics 
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