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MetabolomicsImpact of in vitro hormone treatments on the bibenzyl production of Radula complanata (Untargeted metabolomics)

Bibenzyls are a specialized metabolite class found throughout the plant kingdom. One of the most prolific producers of bibenzyls are liverworts, specifically plants of the Radula genera. These plants possess an incredible diversity of bibenzyls, prenylated bibenzyls and a few (bis)bibenz...

2024-01-10 | MTBLS3563 | MetaboLights
MetabolomicsHost Tree and Geography Induce Metabolic Shifts in the Epiphytic Liverwort Radula complanata
Bryophytes are prolific producers of unique, specialized metabolites that are not found in other plants. As many of these unique natural products are potentially interesting, for example, pharmacological use, variations in the production regarding ecological or environmental conditions have not ofte...
2026-01-29 | MTBLS6740 | MetaboLights
UnknownEffectiveness of Yi-Zhi-An-Shen granules on cognition and sleep quality in older adults with amnestic mild cognitive impairment: protocol for a randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC6701140 | biostudies-literature
ProteomicsMetabolic interplay between Proteus mirabilis and Enterococcus faecalis facilitates polymicrobial biofilm formation and invasive disease
Catheter-associated urinary tract infections (CAUTI) account for 40% of all nosocomial infections and can lead to significant life-threatening complications such as bacteremia. Microbial biofilms play an important role in the development and pathogenesis of CAUTI, and these biofilms are often polymi...
ORGANISM(S): Proteus mirabilis HI4320 Enterococcus faecalis (Streptococcus faecalis) 
2025-05-06 | PXD041693 | Pride
Ionstar Enterococcus faecalis Proteus mirabilis Quantitative proteomics Biofilm 
UnknownBu-Shen-Tian-Jing Formula alleviates oxidative-inflammatory stress in granulosa cells of polycystic ovary syndrome through AGEs-RAGE/NOX4/NF-κB pathway.
Not available
S-EPMC12829069 | biostudies-literature
ProteomicsLocal GTP availability is an essential step in regulation of RAC1 activity and cell invasion
Physiological changes in GTP levels in live cells have never been considered a regulatory step of RAC1 activation because GTP concentrations determined by chromatography or mass spectrometry were shown to be substantially higher than the RAC1 GTP dissociation constant (RAC1-GTP Kd) determined in vit...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD028540 | Pride
Gtp sensors Impdh2 Rac1 Gtp 
ProteomicsIsotopomer analysis of quiescent primary human fibroblasts
To ensure that the pool of precursor amino acids utilized for protein synthesis is completely labeled prior to the first labeling time-point, we conducted an isotopomer analysis. After adaption to media, cells were plated at a density of 500,000 cells per 10 cm plate. 8 days after plating, the confl...
ORGANISM(S): Homo sapiens (Human) 
2016-06-14 | PXD003559 | Pride
Isotopomer analysis 15n labeling 
ProteomicsCyclosporine A Modulates LSP1 Protein Levels in Human B Cells to Attenuate B Cell Migration at Low O2 Levels
Coordinated migration of B cells within and between secondary lymphoid tissues is required for robust antibody responses to infection or vaccination. Secondary lymphoid tissues normally expose B cells to a low O2 (hypoxic) environment. Recently, we have shown that human B cell migration is modulated...
ORGANISM(S): Homo sapiens (Human) 
2022-08-24 | PXD036167 | Pride
Chemotaxis Cxcr4 Human b cells Lsp1 
ProteomicsA mechanism of gene evolution generating mucin function
How novel gene functions evolve is a fundamental question in biology. Mucin proteins, a functionally but not evolutionarily defined group of proteins, allow to study convergent evolution of gene function. By analyzing the genomic variation of mucins across a wide range of mammalian genomes, we propo...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Mus musculus (Mouse) Mustela putorius furo (European domestic ferret) (Mustela furo) Canis familiaris (Dog) (Canis lupus familiaris) Rattus norvegicus (Rat) Sus scrofa domesticus (domestic pig) 
2022-10-15 | PXD033197 | Pride
Adaptation Convergent evolution O-glycosylation Saliva Neofunctionalization Mucins Genomic structural variants Sub-exonic repeats Parallel evolution 
ProteomicsComparative Proteomics Analysis of Exosomes Identifies Key Pathways and Protein Markers Related to Breast Cancer Me-tastasis
The proteomics analysis of circulating exosomes derived from cancer cells represents a promising approach to the elucidation of cell-cell communication and the discovery of putative biomarker candidates for cancer diagnosis and treatment. Nonetheless, the proteome of exosomes derived from cell lines...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD038553 | Pride
Exosomes  breast cancer  metastasis  quantitative proteomics  label-free quantification  ionstar 
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