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ProteomicsA dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line
The immortalized human ReNcell VM cell line represents a reproducible and easy-to-propagate cell culture system for studying the differentiation of neural progenitors. To better characterize the starting line and its differentiation, we assessed protein and phospho-protein levels over a two-week per...
ORGANISM(S): Homo sapiens (Human) 
2019-01-07 | PXD010846 | Pride
Differentiation Phosphoproteomics Neuron Tmt Orbitrap fusion lumos Lc-ms/ms 
UnknownAlpha-synuclein overexpression triggers divergent cellular responses and post-translational modifications in SH-SY5Y and ReNcell VM models.
Not available
S-EPMC12932749 | biostudies-literature
UnknownA dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line.
Not available
S-EPMC6380223 | biostudies-literature
ProteomicsComparative interactome analyses of wild-type and P301L MAPT in two human neuronal cell lines
Protein interactions of the tau protein are of interest in efforts to decipher the mechanisms of cell death in Alzheimer Disease (AD), a subset of frontotemporal dementias (FTD) and other tauopathies. We recently reported on extensive interactions of tau with the ribonucleoproteome and chaperones. A...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD010040 | Pride
Tauopathy Neuron Alzheimer disease Human Frontotemporal dementia Inducible expression Orbitrap Tau Interactome Mapt 
ProteomicsImpact of FGF-2 and FGF-2 containing cell culture supernatants on the intracellular protein composition of ReNcell derived neuron
FGF-2 is an important protein involved in a vast number of molecular pathways and a number of cellular functions including glial cell differentiation and response to axon injury. This protein was found to be present significantly in supernatants of female derived murine oligodendrocyte progenitor ce...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD060285 | Pride
Human neural progenitor cell line Rencell vm Opc cell culture supernatant Fgf-2 Secretome lc-ms/ms 
UnknownAnalysis of the interplay between MeCP2 and histone H1 during <i>in vitro</i> differentiation of human ReNCell neural progenitor cells.
Not available
S-EPMC10769555 | biostudies-literature
TranscriptomicsRole of NTRK2 on ReNcelVM differentiation
The tropomyosin receptor kinase B (TrkB) is encoded by the NTRK2 gene. It belongs to the family of transmembrane tyrosine kinases, which have key roles in the development and maintenance of the nervous system. Brain-derived neurotrophic factor (BDNF) and the neurotrophins NT3 and NT4/5 have high aff...
ORGANISM(S): Homo sapiens 
2023-11-27 | GSE242199 | GEO
TranscriptomicsTranscription profiling of human induced pluripotent stem cells signature and memory retention
Transient expression of two factors, or from Oct4 alone, resulted in efficient generation of human iPSCs. The reprogramming strategy described revealed a potential transcriptional signature for human iPSCs yet retaining the gene expression of donor cells in human reprogrammed cells free of viral and...
ORGANISM(S): Homo sapiens 
2009-12-19 | E-GEOD-18618 | biostudies-arrayexpress
UnknownHigh-content imaging of 3D-cultured neural stem cells on a 384-pillar plate for the assessment of cytotoxicity.
Not available
S-EPMC7152566 | biostudies-literature
UnknownThree dimensional cellular microarray platform for human neural stem cell differentiation and toxicology.
Not available
S-EPMC4090259 | biostudies-literature
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