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ProteomicsProteomic characterization of the pellicle of Toxoplasma gondii
Toxoplasma gondii is an obligate intracellular parasite. The ability to invade cells and proliferate successfully is given by the machinery found in the pellicle of the parasite, the pellicle is a complex of three membranes. Despite the importance of the pellicle in the biology of Toxoplasma, its pr...
ORGANISM(S): Toxoplasma gondii 
2021-02-16 | PXD022398 | Pride
Toxoplasma Mass spectrometry Protein quantification Adhesion Srs Pellicle 
ProteomicsExpression profiles of kidney mitochondrial proteome during the progression of the unilateral ureteral obstruction: focus on energy metabolism adaptions.
Obstructive nephropathy (ON) is a common clinical entity caused by different etiologies such as urolithiasis, prostatic hyperplasia in males, tumors, congenital stenosis, and others. Unilateral ureteral obstruction (UUO) in rodents is an experimental model widely used to explore the pathophysiology ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-18 | PXD036205 | Pride
Kidney fibrosis Mitochondria proteome Energy metabolism. Unilateral ureteral obstruction (uuo) 
ProteomicsMitochondrial proteomics reveals reductive metabolism dependent on glutamine in fibroblasts of idiopathic pulmonary fibrosis under hypoxia
Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), is a chronic disease characterized not only by a transcriptionally active signature associated with hypoxia but also by feedback loops that may underlie disease progression. IPF fibroblasts are known to contribute to disease by th...
ORGANISM(S): Homo sapiens (Human) 
2025-11-05 | PXD064472 | Pride
Lung fibroblasts Mitochondria Proteome Ipf 
ProteomicsMass spectrometry of excretory/secretory products (ectosomes, exosomes, and soluble proteins) secreted by Toxoplasma gondii tachyzoites isolated from an infected murine model.
Toxoplasma gondii is an intracellular parasite that infects all nucleated cells; to date, this organism is considered as one of the most successful parasites in the world. During infection, internalization, and proliferation the parasite excretes/secretes a high number of proteins, several of them w...
ORGANISM(S): Toxoplasma gondii GT1 
2019-08-29 | PXD013767 | Pride
Toxoplasma gondii. Quantification Excretory/secretory products Mass spectrometry Ectosomes Exosomes 
ProteomicsIdentification of dystrophin Dp71dΔ71 associated proteins in PC12 cells by quantitative proteomics
Dystrophin Dp71 is the main product of the DMD (Duchenne muscular dystrophy) gene in the brain. Dystrophin Dp71 is essential for the development of the nervous system and its alteration is associated with intellectual disability. Different isoforms of Dp71, with different subcellular locations, are ...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-11-01 | PXD021886 | Pride
Quantitative proteomics. Dp71 Protein interaction Dmd 
ProteomicsProteomic characterization and protective effect against brain ischemia produced by adult mouse neural progenitor cells-derived extracellular vesicles.
Hypoxia produced by stroke activates the proliferation of neural progenitor cells (NPC) in the subventricular zone of the adult mouse brain. Newly generated cells seem to participate in the protection of the ischemic brain through the release of extracellular vesicles (EVs) that might target differe...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-14 | PXD033915 | Pride
Stroke Extracellular vesicles Neural progenitor cells Neurodegeneration 
ProteomicsLabel free mass spectrometry quantification of differentially expressed proteins in an atypical presentation of Autoimmune Lymphoproliferative Syndrome.
Autoimmune lymphoproliferative syndrome (ALPS) is a rare disease characterized among others things by chronic massive, nonmalignant lymphoadenopathy and splenomegaly. ALPS has been defined as a defect in the lymphocyte apoptotic pathway and is associate with inherited mutations in the FAS, Fas ligan...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD013289 | Pride
Caspase10 Fas Fasl Apoptosis Autoimmune lymphoproliferative syndrome (alps) Mutation Label-free quantitation. 
ProteomicsLabel-free based DIA quantification of a lung cancer cell line and its potential application in nanomedicine.
Lung cancer is the uncontrolled growth of abnormal cells in the lungs, which can form tumors and interfere with the functioning of the lung. This disease is registered worldwide as the most common type of cancer in men as well as the most common cause of death; besides lung cancer mortality in women...
ORGANISM(S): Homo sapiens (Human) 
2022-08-19 | PXD015405 | Pride
Mrc5 Mass spectrometry Small cell lung cancer Label-free H69ar 
UnknownHeart failure in Europe: Guideline-directed medical therapy use and decision making in chronic and acute, pre-existing and de novo, heart failure with reduced, mildly reduced, and preserved ejection fraction - the ESC EORP Heart Failure III Registry.
Not available
S-EPMC11683873 | biostudies-literature
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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