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UnknownA Computable Electronic Health Record ARDS Classifier and the Association Between the <i>MUC5B</i> Promoter Polymorphism and ARDS in Critically Ill Adults.
Not available
S-EPMC12867120 | biostudies-literature
ProteomicsCardiomyocyte-intrinsic somatic mtDNA mutations induce an OXPHOS-dependent immune response and promote progressive heart failure
Mitochondrial DNA (mtDNA) mutations accumulate with age, but their mechanistic contribution to ageing remains unclear. The classical mtDNA mutator mouse expresses a proofreading-deficient mtDNA polymerase (POLGD257A) and accumulates mtDNA mutations across all tissues leading to premature ageing. How...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-28 | PXD080411 | Pride
Mtdna Heart Mouse Liver Mitochondria Spleen 
ProteomicsCDKL1 risk variants predispose to a connective tissue disorder with thoracic aortic aneurysm and dissection
Genetic factors are fundamental in the etiology of thoracic aortic aneurysm and dissection (TAAD), but the genetic cause is detected in only about 30% of cases. To define unreported TAAD-associated sequence variants, exome and gene panel sequencing was performed in 323 patients. We identified hetero...
ORGANISM(S): Homo sapiens (Human) 
2025-09-09 | PXD048044 | Pride
Cdkl1 Cgmp signaling Thoracic aortic aneurysm and dissection Arterial aneurysm and dissection Hereditary aortopathy Connective tissue disorder 
ProteomicsSWATH analysis of 1433B_HUMAN affinity purifications from HEK293 cells after time course treatment with IGF1
Protein complexes and protein interaction networks are essential mediators of most biological functions. Complexes supporting transient functions such as signal transduction processes are frequently subject to dynamic remodeling. Currently, the majority of studies into the composition of protein com...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-20 | MSV000082833 | MassIVE
UnknownNew primate genus from the Miocene of Argentina.
Not available
S-EPMC1459373 | biostudies-literature
ProteomicsInference and quantification of peptidoforms in large sample cohorts by SWATH-MS: Twin blood plasma quantitative variance components
This data set represents a reanalysis of human blood plasma samples measured by SWATH-MS of 36 pairs of monozygotic and 22 pairs of dizygotic twins that were sampled at two longitudinal time points (Liu et al., 2015, PMID:25652787). The data were used to determine the overall quantitative variabilit...
ORGANISM(S): Homo sapiens (Human) 
2017-06-06 | PXD004574 | Pride
Ipf Openswath Blood plasma Ptm Human 
UnknownGlobal, pathway and gene coverage of three Illumina arrays with respect to inflammatory and immune-related pathways.
Not available
S-EPMC6871524 | biostudies-literature
ProteomicsInference and quantification of peptidoforms in large sample cohorts by SWATH-MS: PTM-SWATH-MS Gold Standard data set
The PTM-SWATH MS Gold Standard data set consists of a previously published (Soste et al., 2014, PMID:25194849) set of 579 unpurified, synthetic, heavy-isotope labeled phosphopeptides (Thermo Scientific Biopolymers). These phosphopeptides represent biologically relevant sequences from S. cerevisiae p...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2017-06-12 | PXD004573 | Pride
Ipf Openswath Synthetic phosphopeptides Gold standard data set Human Yeast 
ProteomicsAP-SWATH analysis reveals a direct involvement of VCP/p97 in integrated stress response signalling through CReP/PPP1R15B degradation
The ubiquitin-directed AAA-ATPase VCP/p97 facilitates degradation of misfolded proteins in diverse cellular stress response pathways. Resolving the complexity of dynamic interactions with hosts of accessory proteins and substrates has therefore been a major challenge. Here, we used affinity-purifica...
ORGANISM(S): Homo sapiens (Human) 
2018-04-04 | PXD007876 | Pride
Integrated stress response Ap-swath P97 
UnknownGoats (Capra hircus) From Different Selection Lines Differ in Their Behavioural Flexibility.
Not available
S-EPMC8844551 | biostudies-literature
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