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TranscriptomicsMurine primary dendritic cells: Control vs. Influenza-infected vs. polyI:C stimulated.
MIcroRNA expression profiling of primary murine splenic dendritic cells (Flt3L expanded) comparing untreated cells to cells infected with Influenza A or stimulated with polyI:C in vitro. Three-condition experiment, Influenza A/PR/8/34 virus MOI=10 vs polyI:C 30 ug/mL vs. mock treated; RNA collected ...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-36316 | biostudies-arrayexpress
ProteomicsChemical and Random Additive Noise Elimination (CRANE) - case_study - multicenter_dataset
The effectiveness of the novel electrospray ionisation - liquid chromatography mass spectrometry (ESI-LC-MS) data de-noising technique, CRANE, is demonstrated by denoising the MS1 and all the MS2 windows of the multicentre, data-independent acquisi-tion (DIA) MS dataset from Navarro, et al. (2016).
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2021-07-26 | PXD020529 | Pride
Lc-msms Random noise Chemical noise Denoise Baseline noise Dia 
ProteomicsSystems pharmacology dissection of cholesterol regulation reveals determinants of large pharmacodynamic variability between cell lines
In individuals, heterogeneous drug response phenotypes result from a complex interplay of dose, drug specificity, genetic background, and environmental factors, thus challenging our understanding of the underlying processes and optimal use of drugs in the clinic. Here, we use mass spectrometry-based...
ORGANISM(S): Homo sapiens (Human) 
2017-12-07 | PXD005955 | Pride
Cholesterol regulation T0901317 Cholesterol homeostasis Hela kyoto Gw3965 Srebp Lxr Hek293 Atorvastatin Srebp1 Srebp2 Npc1 Ldlr Huh7 Hmgcs1 Hepg2 
TranscriptomicsSCL006,icSARS CoV Urbani or icSARS Bat SRBD (spike receptor binding domain from the wild type strain Urbani to allow for infection of human and non-human primate cells) infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV or the icSARS deltaORF6 mutant. Calu-3 cells were infected with either icSARS CoV or the cSARS Bat SRBD strain at MOI of 1.0. Cells samples were collected at 0, 7, 1...
ORGANISM(S): Homo sapiens 
2012-05-06 | E-GEOD-37827 | biostudies-arrayexpress
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
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