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MetabolomicsMetabolic responses of rice cultivars with different tolerance to combined heat and drought stress under field conditions
Rice is susceptible to both heat and drought stress, in particular during flowering and grain filling, when both grain yield and quality may be severely compromised. However, under field conditions, these two stresses rarely occur separately. Under well-watered conditions, plants avoid heat stress b...
2019-04-25 | MTBLS801 | MetaboLights
ProteomicsCD209L/L-SIGN N-Glycosylation and N-Glycosylation Site Occupancy
CD209L is a membrane glycoprotein with known glycan-binding properties and it also contains 2 N-glycosylation sequons at sites N92 and N361. Treatment with PNGase F in the presence of H218O, which removes N-linked glycans and isotopically labels the formerly-glycosylated site, confirmed that both un...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021309 | Pride
Human cd209l Dc-sign N-glycosylation 
ProteomicsNaive and DSS Murine Colon TMTpro bRP fractionation N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060852 | Pride
Mouse Protease Fractionation Legumain N-terminomics Colon Colitis 
ProteomicsMurine colon HUNTER N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060854 | Pride
Legumain Mouse Colon Colitis Hunter 
UnknownStudy protocol: combined N-of-1 trials to assess open-label placebo treatment for antidepressant discontinuation symptoms [FAB-study].
Not available
S-EPMC10576328 | biostudies-literature
TranscriptomicsGene expression in epithelial and non-epithelial cells of renal origin
We aimed to define epithelial-specific genes in the kidney. In the developing mouse kidney at E12.5 epithelial cells are restricted to the ureteric bud, while mesenchymal cells surrounding the ureteric bud are non-epithelial. The mouse renal epithelial cell line mIMCD-3 was used to represent kidney ...
ORGANISM(S): Mus musculus 
2010-09-23 | E-GEOD-24295 | biostudies-arrayexpress
ProteomicsN-linked glycosylation enrichment for in-depth cell surface proteomics and the classification of diffuse large B-cell lymphoma subtypes
The classification of histologically similar yet molecularly distinct tumors into specific subtypes remains a clinically challenging task. Classification of such tumors into distinct entities based on their cell surface protein expression profiles has been hindered by the lack of an unbiased global...
ORGANISM(S): Homo sapiens (Human) 
2016-08-25 | PXD000332 | Pride
N-linked glycosylation Diffuse large b-cell lymphoma Glycoproteome 
ProteomicsPhosphoproteomic analysis of T cell receptor stimulation-induced changes in human primary CD4+CD25- T cells in the absence or presence of regulatory T cells.
Regulatory T cells (Tregs) suppress other immune cells and are indispensable for human health, yet the molecular mechanisms of suppression remain incompletely understood. Tregs can suppress proliferation and cytokine production of CD4+CD25- conventional T cells (Tcons). We previously demonstrated th...
ORGANISM(S): Homo sapiens (Human) 
2017-08-28 | PXD004291 | Pride
Co-cultures Regulatory t cells (tregs) Ti-imac Human cd4+ t cells Phosphoproteomics 
GenomicsGenome-wide binding profiles of KLF3 and KLF3 mutants in MEF cells
Transcription factors are often regarded as being comprised of a DNA-binding domain and a functional domain. The two domains are considered separable and autonomous, with the DNA-binding domain directing the factor to its target genes and the functional domain imparting transcriptional regulation. W...
ORGANISM(S): Mus musculus 
2013-10-17 | E-GEOD-44748 | biostudies-arrayexpress
UnknownDetermining the Ensemble <i>N</i>-Representability of Reduced Density Matrices.
Not available
S-EPMC12805516 | biostudies-literature
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