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TranscriptomicsComparison of post-mortem tissue from brain BA10 region between schizophrenic and control patients.
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Schizophrenia is a severe psychiatric disorder with a world-wide prevalence of 1%. The pathophysiology of the illness is not understood, but is thought to have a strong...
ORGANISM(S): Homo sapiens 
2009-08-13 | E-GEOD-17612 | biostudies-arrayexpress
TranscriptomicsComparison of post-mortem tissue from Brodman Brain BA22 region between schizophrenic and control patients
Transcriptional analysis of the superior temporal cortex (BA22) in schizophrenia: Pathway insight into disease pathology and drug development Schizophrenia is a highly debilitating psychiatric disorder which is known to have heritable genetic and environmental components. To gain some insight into t...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-21935 | biostudies-arrayexpress
ProteomicsProteomic profiling of WT and KO for DPP3 Mus musculus splenocites, treated (and not) with LPS
Effective host defense against infection relies on the tight coordination of immune activation, metabolic adaptation, and redox control, yet how these processes are integrated remains incompletely understood. Here, we identify dipeptidyl peptidase 3 (Dpp3) as a negative regulator of antimicrobial im...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-21 | PXD074007 | Pride
Mus musculus Immunity Splenocites 
ProteomicsHuman dental calculus LC-MS/MS
The purpose of this study was to investigate oral microbiome and host proteins in archaeological human dental tissues using a shotgun proteomics approach. The research focuses on dental calculus (mineralized plaque), dentine, a carious lesion, and an alveolar bone abscess from the medieval site of D...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Ovis 
2014-01-29 | PXD000412 | Pride
Human Caries Ltq-orbitrap velos Cementum Maxis uhr-qq-tof Medieval Dentine Dental calculus Cattle Abscess Bone Dental plaque Q-exactive hybrid quadrupole orbitrap Sheep Archaeological Periodontitis 
UnknownNeural network analysis of sleep stages enables efficient diagnosis of narcolepsy.
Not available
S-EPMC6283836 | biostudies-literature
ProteomicsQuantitative proteome profiling of parental cell lines used in the RESOLUTE project (https://re-solute.eu).
To enable successful SLC function deorphanization we aimed to select a minimal number of cell lines covering expression of as many SLCs as possible. Based on a publicly available RNA-Seq dataset of 675 cell lines (Klijn C. et al, Nat. Biotechnol. 2015) we selected a set of 6 adherent human cell line...
ORGANISM(S): Homo sapiens (Human) 
2024-04-29 | PXD051747 | Pride
Lc-msms Solute carriers Resolute Human Lfq Slc 
UnknownValidation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease.
Not available
S-EPMC4283618 | biostudies-literature
UnknownPrediction of protein assemblies, the next frontier: The CASP14-CAPRI experiment.
Not available
S-EPMC8616814 | biostudies-literature
UnknownImpact of AlphaFold on structure prediction of protein complexes: The CASP15-CAPRI experiment.
Not available
S-EPMC10841881 | biostudies-literature
ProteomicsSEC-SWATH-MS HEK293 - Complex-centric proteome profiling by SEC-SWATH-MS
Increasingly, biochemical co-fractionation-based approaches are used to study interactomes and protein complexes at high throughput. The devised methods facilitate the qualitative assignment and prediction of hundreds of putative cellular assemblies in one experiment and without dependency on geneti...
ORGANISM(S): Homo sapiens (Human) 
2019-01-11 | PXD007038 | Pride
Size exclusion chromatography Mass spectrometry Swath Protein complexes 
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