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GenomicsPolycomb repression works without Siesta [ChIP]
Polycomb repression works without Siesta [ChIP]
PRJNA1291712 | ENA
GenomicsPolycomb repression works without Siesta [TRIP]
Polycomb repression works without Siesta [TRIP]
PRJNA1292739 | ENA
ProteomicsSystem-wide identification of enzyme substrates by thermal analysis (SIESTA)
Despite the immense importance of enzyme-substrate reactions, there is a lack of generic and unbiased tools for identifying the molecular components participating in these reactions on a cellular level. Here we developed a universal method called System-wide Identification of Enzyme Substrates by Th...
ORGANISM(S): Homo sapiens (Human) 
2021-01-11 | PXD014445 | Pride
Proteomics Post-translational modification Target Thermal stability Lc/ms Akt1 Trxr1 Parp10 Artd10 Rac-alpha serine threonine protein kinase Txnrd1 
ProteomicsSystem-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
Despite the immense importance of enzyme-substrate reactions, there is a lack of generic and unbiased tools for identifying and prioritizing substrate proteins which are modulated in the structural and functional levels through modification. Here we describe a high-throughput unbiased proteomic meth...
ORGANISM(S): Homo sapiens (Human) 
2021-01-11 | PXD021915 | Pride
Pulldown Lc-ms Hct116 Parp10 
ProteomicsSystem-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
Despite the immense importance of enzyme-substrate reactions, there is a lack of generic and unbiased tools for identifying and prioritizing substrate proteins which are modulated in the structural and functional levels through modification. Here we describe a high-throughput unbiased proteomic meth...
ORGANISM(S): Homo sapiens (Human) 
2021-01-11 | PXD021916 | Pride
Siesta Hela Akt1 Enzyme Phpsphoproteomics Thermal profiling 
UnknownSiesta behavior and genetics interact to influence obesity risk.
Not available
S-EPMC11664305 | biostudies-literature
UnknownTime-dependent cortical responses to siesta disruption in male mice.
Not available
S-EPMC12411512 | biostudies-literature
OtherPolycomb repression works without Siesta [TRIP]
Polycomb group proteins are essential for epigenetic repression of developmental genes. They act as multi-subunit complexes whose biochemical functions are yet to be fully characterised. One of the complexes, canonical Polycomb Repressive Complex 1 (PRC1), acts as an E3 ligase, depositing a single u...
ORGANISM(S): Drosophila melanogaster 
2025-07-17 | GSE302873 | GEO
GenomicsPolycomb repression works without Siesta [ChIP]
Polycomb group proteins are essential for epigenetic repression of developmental genes. They act as multi-subunit complexes whose biochemical functions are yet to be fully characterised. One of the complexes, canonical Polycomb Repressive Complex 1 (PRC1), acts as an E3 ligase, depositing a single u...
ORGANISM(S): Drosophila melanogaster 
2025-07-17 | GSE302678 | GEO
UnknownThe Siesta Habit is Associated with a Decreased Risk of Rupture of Intracranial Aneurysms.
Not available
S-EPMC5595157 | biostudies-literature
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