Sort   by:  
 Page size 
ProteomicsLabel-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080718 | MassIVE
ProteomicsQuantitative proteome analysis of plasma microparticles for characterization of HCV-induced hepatic cirrhosis and hepatocellular carcinoma
A quantitative label-free proteome analysis was performed using plasma samples from 22 hepatitis-C virus (HCV)-induced liver cirrhosis patients, 16 HCV-positive hepatocellular carcinoma patients with underlying cirrhosis and 18 healthy controls. Plasma microparticles (PMPS) were isolated using ultra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-12 | MSV000085094 | MassIVE
ProteomicsQuantitative proteome analysis of hepatocellular carcinoma tissue
Hepatocellular carcinoma (HCC) is one of the most aggressive tumors and the treatment outcome of this disease is improved when the cancer is diagnosed at early stages. This requires biomarkers allowing for an accurate and early tumor diagnosis. To identify potential markers for such applications we ...
ORGANISM(S): Homo sapiens (Human) 
2016-04-13 | PXD002171 | Pride
Human Srm Tissue Label-free proteomics Hepatocellular carcinoma Bimarkers Mrm Multiple reaction monitoring Early diagnosis biomarker Versican. Targeted proteomics Selected reaction monitoring 
ProteomicsQuantitative analysis of proteome dynamics in a long-term asthma mouse model
Asthma bronchiale is an inflammatory disease of the respiratory airways and a major factor of increasing health care costs worldwide. The molecular actors leading to asthma are not fully understood and require further investigation. The aim of this study was to monitor the proteome during asthma dev...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-11 | PXD011159 | Pride
Mouse model Asthma bronchiale Time-course model Ovalbumin model 
ProteomicsQuantitative Secretome Analysis of Activated Jurkat Cells
A quantitative label-free secretome analysis protocol using a click chemistry-based approach for the enrichment of secreted glycoproteins was adapted for and applied to a T cell model. There, Jurkat cells were activated via PMA/ionomycin and the dynamic modulation of the T cell secretome was investi...
ORGANISM(S): Homo sapiens (Human) 
2016-10-10 | PXD004280 | Pride
T cell model Jurkat Quantitative label-free lc-ms/ms Secretome 
ProteomicsQuantitative proteome analysis of plasma microparticles for characterization of HCV-induced hepatic cirrhosis and hepatocellular carcinoma
A quantitative label-free proteome analysis was performed using plasma samples from 22 hepatitis-C virus (HCV)-induced liver cirrhosis patients, 16 HCV-positive hepatocellular carcinoma patients with underlying cirrhosis and 18 healthy controls. Plasma microparticles (PMPS) were isolated using ultra...
ORGANISM(S): Homo sapiens (Human) 
2017-06-21 | PXD005777 | Pride
Plasma microparticles Liver cirrhosis Hepatitis c virus Label-free proteomics Hepatocellular carcinoma 
ProteomicsSpectral histopathology supported laser capture microdissection and quantitative proteome analysis of diffuse malignant mesothelioma
FTIR based spectral histopathology was used for label-free classification of tumor tissue sections. The regions of interest were identified and annotated with high spatial resolution. The spatial information was used for automated laser capture microdissection of relevant tissue areas. Subsequently,...
ORGANISM(S): Homo sapiens (Human) 
2017-03-31 | PXD004818 | Pride
Diffuse malignant mesothelioma Ftir Colorectal carcinoma Laser capture microdissection Infrared spectral histopathology 
ProteomicsQuantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection
We established a new protocol for negative immunomagnetic isolation of murine primary Type II alveolar epithelial cells (AEC II) yielding untouched primary murine AEC II. AEC II were collected from mice 24h after Aspergillus fumigatus or mock infection (9 replicates per experimental group) and analy...
ORGANISM(S): Mus musculus (Mouse) 
2017-10-05 | PXD005834 | Pride
Infection Aspergillus fumigatus Lung Type ii alveolar epithelial cells Aspergillosis Primary cells 
ProteomicsA systematic comparison of label-free, SILAC and TMT techniques to study early adaption towards inhibition of EGFR signaling in the colorectal cancer cell line Difi
The epithelial growth factor receptor (EGFR) signalling network plays an essential role inproliferation and survival of colorectal cancer cells. For this reason, EGFR is targeted using therapeutic antibodies blocking EGFR signalling (e.g. cetuximab). However, anti-EGFR therapy is rarely curative as ...
ORGANISM(S): Homo sapiens (Human) 
2019-12-11 | PXD014565 | Pride
Phosphoproteomics Tmt Anti-egfr therapy Colorectal cancer Silac Mapk Label-free Erbb3 Adaptive mechanism Cetuximab 
ProteomicsIntegrated FTIR imaging and proteomics for identification of a candidate histochemical biomarker in bladder cancer
A quantitative label-free proteome analysis of cystitis and high-grade bladder cancer tissue priorly annotated and isolated via FTIR-guided lasermicrodissection.
ORGANISM(S): Homo sapiens (Human) 
2019-08-13 | PXD009203 | Pride
Human Tissue Bladder Lc-ms/ms 
Sort   by:  
 Page size