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identification of lysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
ORGANISM(S): Proteus Mirabilis Atcc 29906 Escherichia Coli 
In this project, we first screened proteomics of OLP/OLL tissue-derived extracellular vesiclesEVs
ORGANISM(S): Homo Sapiens 
2021-06-25 | PXD026938 |
We report a DNA templated chemistry and photo-crosslinking based method to detect the readers of mRNA modification. By use of N6-methyladenosine (m6A), we illustrated that this method can be successfully utilized for labelling and enriching the readers of mRNA modification, as well as for the discov...
ORGANISM(S): Homo Sapiens 
Five tandem-domain reader proteins (BPTF, CBP, TAF1, TRIM24 and TRIM33) were designed and prepared as the enriched probes, and a group of binding proteins from HEK293T were enriched by domain probes and identified by HPLC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2020-01-13 | PXD014909 | Pride
Firstly, the back muscle samples of Tibetan sheep of the same age were collected for subsequent proteomic analysis. The integrated and analyzed results aimed to identify proteins and pathways associated with meat quality and growth regulation in sheep, thereby providing a theoretical foundation for...
ORGANISM(S): Ovis Aries 
Lysine lactylation (Kla) links metabolism and gene regulation and plays a key role in multiple biological processes. We report that HBO1 functions as a lysine lactyltransferase to regulate transcription. Quantitative proteomic analysis further revealsed 95 endogenous Kla sites targeted by HBO1, with...
ORGANISM(S): Homo sapiens (Human) 
2024-04-13 | PXD051415 | Pride
SILAC experiments profiling of the proteome of WT and CobB KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030345 |
SILAC experiments profiling of the proteome of WT and YiaC KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030346 |
We identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead...
ORGANISM(S): Homo Sapiens 
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