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The UTX/KDM6A gene encodes the UTX histone H3K27 demethylase, which plays an important role in mammalian development and is frequently mutated in cancers and particularly, in urothelial cancers. Using BioID technique, we explored the interactome of different UTX isoforms.
ORGANISM(S): Homo sapiens (Human) 
2024-01-28 | PXD041254 | Pride
Time series expression profile of yeast cells grown at high glucose and shifted to low glucose containing medium. Lowess normalized data in raw data files.
ORGANISM(S): Saccharomyces cerevisiae 
Chromatin modifiers, transcription factors and cofactors regulate gene expression through engagement with chromatin and DNA, which can be detected by a variety of genomic techniques. Here, we describe a novel method ‘greenCUT&RUN’ for genome-wide profiling of transcription regulatory factors, which ...
ORGANISM(S): Homo sapiens (Human) 
2021-01-13 | PXD021089 | Pride
Loss-of-function mutations of the multiple endocrine neoplasia type 1 (MEN1) gene are causal to the MEN1 tumor syndrome, but they are also commonly found in sporadic pancreatic neuroendocrine tumors and other types of cancers. The MEN1 gene product, menin, is involved in transcriptional and chromati...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD031928 | Pride
wildtype and mot1-1 mutant expression profle
ORGANISM(S): Saccharomyces cerevisiae 
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