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ProteomicsCupiennius salei Hyal LC-MSMS - Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei
Hyaluronidases are important venom components by acting as spreading factor of neurotoxins. In several studies this spreading effect was tested on vertebrate tissue. However, data about the spreading activity on invertebrates, which are the main prey organisms of spiders, are lacking. In this study,...
ORGANISM(S): Cupiennius salei (American wandering spider) 
2015-12-10 | PXD002489 | Pride
Venom Spider Cupiennius salei Hyaluronidase 
ProteomicsDifferential proteomes in the vitreous of mice with a chronic hypoxic response in photoreceptors
Reduced oxygenation of photoreceptors and the RPE in the ageing eye may be a risk factor for the development of both neovascular and dry AMD. Chronic activation of the molecular response to hypoxia in RPE or photoreceptors leads to retinal degeneration that depends on hypoxia inducible transcription...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-12 | PXD008911 | Pride
Retinal degeneration Vitreous Cones Rods Hypoxic response Amd Shot-gun proteomics 
ProteomicsThe Proteomic Landscape in the Vitreous of Patients With Age-Related and Diabetic Retinal Disease
In contrast to neovascular age-related macular degeneration (nAMD), no treatment option exists for dry AMD. The identification of specific biomarkers is required to facilitate diagnosis and therapy of dry AMD. We thus measured the proteome of 34 vitreous humor samples (dry AMD: n = 6, nAMD: n = 10, ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-23 | PXD008354 | Pride
Pdr Proliferative diabetic retinopathy Dry amd Age-related macular degeneration Neovascular amd Epiretinal membrane Vitreous proteome Human Biomarker Vitreous humor Namd Erm 
ProteomicsLabel-free shotgun proteomics of S. cerevisiae producing starch-like glucans
The synthesis of starch-like glucans can be reconstituted in S. cerevisiae using the genes from Arabidopsis thaliana: heterologous expression of SS1 to SS4, BE2, BE3, ISA1, and ISA2, together with a bacterial ADPglucose pyrophosphorylase gene for substrate provision in yeast strain 29, yielded insol...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-05 | PXD032241 | Pride
Lc-ms/ms Progenesisqi Yeast 
ProteomicsThe landscape of renal protein cysteine acylation in mice with kidney injury induced by a high fat diet
Background. Dyslipidemia is associated with chronic kidney disease (CKD). It has been shown that inhibition of β-oxidation and lipid accumulation are common threats in the onset of kidney injury and conducive to fibrosis. We characterized the S-acylated proteome of kidneys from mice with diet-induce...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-21 | PXD052634 | Pride
Hf-diet Dia Whole proteome Palmitoylated Mus musculus Chow-diet Proteomics 
ProteomicsA synthetically methylotrophic Escherichia coli as a chassis for bioproduction
Proteome characterization of three E. coli strains: a methanol-dependent strain (MEvo1-0) and two synthetically methylotrophic strains (MEcoli_ref_1, MEcoli_ref_2)
ORGANISM(S): Escherichia coli 
2024-02-08 | PXD046243 | Pride
Synthetic biology Metabolic engineering Synthetic methylotrophy Biotechnology E. coli 
UnknownBronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe.
Not available
S-EPMC6275519 | biostudies-literature
ProteomicsHuman dental calculus LC-MS/MS
The purpose of this study was to investigate oral microbiome and host proteins in archaeological human dental tissues using a shotgun proteomics approach. The research focuses on dental calculus (mineralized plaque), dentine, a carious lesion, and an alveolar bone abscess from the medieval site of D...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) Ovis (ncbitaxon:9935) 
2016-10-23 | MSV000080279 | MassIVE
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