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TranscriptomicsmRNA expression data of 62 human medulloblastoma tumors
To identify molecular subtypes of medulloblastoma we have profiled a series of 62 medulloblastoma tumors. Unsupervised hierarchical cluster analysis of these data identified 5 distinct molecular subtypes. Manuscript submitted. Title: Identification of medulloblastoma subtypes with distinct genetic p...
ORGANISM(S): Homo sapiens 
2008-09-02 | E-GEOD-10327 | biostudies-arrayexpress
ProteomicsIdentification of biotinylated proteins through pull-down: ID and label-free quantification (Identification of TTP-interactome in RAW264.7 cells by TurboID proximity labelling).
Identification of biotinylated proteins through pull-down. RAW264.7 cells stably expressing a Dox-inducible TurboID-TTP fusion protein were treated with LPS or Epoxomicin for 4 h, followed by 15 min of biotin labeling in the cell medium. TurboID without fusion was used as a control.
ORGANISM(S): Mus musculus (Mouse) 
2023-03-24 | PXD036714 | Pride
Lps Ttp Raw264.7 Turboid Macrophages Epoxomicin Biotin 
ProteomicsQuantitative proteomics to systematically assess protein changes after HUWE1 knockout, in RAW264.7-Dox-Cas9.
Quantitative proteomics to systematically assess protein changes after HUWE1 knockout, in RAW264.7-Dox-Cas9.
ORGANISM(S): Mus musculus (Mouse) 
2023-03-22 | PXD036715 | Pride
Lps Ttp Raw264.7 Psmb7 Macrophages Huwe1 
TranscriptomicsInactivation of CDK2 is synthetic lethal to MYCN-overexpressing cancer cells
Two genes have a synthetic lethal relationship when silencing or inhibition of one gene is only lethal in the context of a mutation or activation of the second gene. This situation offers an attractive therapeutic strategy, as inhibition of such a gene will only trigger cell death in tumor cells wit...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-16480 | biostudies-arrayexpress
UnknownAccelerating Brain Imaging Using a Silent Spatial Encoding Axis.
Not available
S-EPMC9544176 | biostudies-literature
TranscriptomicsEffect of genomic imbalances on gene expression in rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common paediatric soft-tissue sarcoma and resembles developing skeletal muscle. Specific genomic alterations including translocations, deletions and amplification events have been associated with the alveolar and embryonal subtypes of RMS. Characterizing these c...
ORGANISM(S): Homo sapiens 
2009-06-04 | E-GEOD-8840 | biostudies-arrayexpress
UnknownThe Lipid Activation Mechanism of a Transmembrane Potassium Channel.
Not available
S-EPMC8281327 | biostudies-literature
UnknownCathepsin L promotes chemresistance to neuroblastoma by modulating serglycin.
Not available
S-EPMC9484481 | biostudies-literature
TranscriptomicsIn vitro expansion of human gastric epithelial stem cells and their primary response to bacterial infection
We previously established long-term 3D organoid culture systems for several murine tissues (intestine, stomach, pancreas and liver) as well as human intestine and pancreas. Here, we describe culture conditions to generate long-term 3D culture from human gastric stem cells. The technology can be appl...
ORGANISM(S): Homo sapiens 
2014-10-13 | E-GEOD-60557 | biostudies-arrayexpress
UnknownConstruction and evaluation of an antibody phage display library targeting heparan sulfate.
Not available
S-EPMC7329785 | biostudies-literature
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