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ProteomicsMiddle Pleistocene protein sequences from the rhinoceros genus Stephanorhinus and the phylogeny of extant and extinct Middle/Late Pleistocene Rhinocerotidae.
Characterization of Middle Pleistocene rhinoceros proteins and the phylogenetic relationships between extinct and extanct rhinoceros was investigated by obtaining ancient protein data for two extinct rhinoceros genera (Coelodonta antiquitatis and Stephanorhinus sp.).
ORGANISM(S): Rhinocerotidae Coelodonta antiquitatis (woolly rhinoceros) 
2017-02-02 | PXD005534 | Pride
Ancient proteins Collagen Non-collagenous proteins Rhinocerotidae 
ProteomicsA late Middle Pleistocene Denisovan mandible from the Tibetan Plateau
A dentine sample from a previously unknown hominin specimen deriving from the Tibetan Plateau was analyzed using LC-MS/MS in order to characterize its proteome, protein damage characteristics, and phylogenetic affinities to known Late Pleistocene hominin clades (humans, Neanderthals, Denisovans).
ORGANISM(S): Homo 
2019-05-08 | PXD011377 | Pride
Zooms Middle pleistocene Hominin Palaeoproteomics 
ProteomicsAncient proteins resolve the evolutionary history of Darwin's South American ungulates
The project aimed to characterize the collagen type I (COL1) sequences from Pleistocene Macrauchenia sp. and Toxodon sp. bone samples, and by comparison with existing COL1 sequences available from genomic sources establish the phylogenetic position of both extinct species. In order to resolve their ...
ORGANISM(S): unidentified Equus Orycteropus afer (Aardvark) Cyclopes didactylus (Silky anteater) (Myrmecophaga didactyla) Hippopotamus amphibius (Hippopotamus) Tapirus terrestris (Lowland tapir) (Brazilian tapir) Mylodon darwinii (Giant ground sloth) 
2015-03-19 | PXD001411 | Pride
Lc-ms/ms Macrauchenia Toxodon Bruker maxis hd De novo collagen sequencing Pleistocene Thermo scientific hybrid quadrupole-orbitrap 
ProteomicsA Pleistocene hominin enamel proteome from Homo antecessor
Hominin relationships and their dispersal throughout Eurasia during the Early and Middle Pleistocene are highly debated. The relationships between Early and Middle Pleistocene hominins, like Homo antecessor and Homo erectus, and hominin species that dominate the Late Pleistocene fossil record, like ...
ORGANISM(S): Homo 
2020-04-02 | PXD014342 | Pride
Enamel Hominins Phosphorylation Palaeoproteomics Lc-ms/ms 
ProteomicsMulti-protease analysis of Pleistocene bone proteomes
Palaeoproteomics of skeletal tissues has the potential to provide new insights into the evolutionary relationships between globally distributed hominin fossils across the Pleistocene. The use of alternative or additional proteases has the potential to increase both proteome size and protein. However...
ORGANISM(S): Homo Equidae 
2020-10-13 | PXD018264 | Pride
Proteases Neanderthals Bone Pleistocene 
ProteomicsEnamel proteome shows that Gigantopithecus was an early diverging pongine
Gigantopithecus blacki was a giant hominid that inhabited Southeast Asia during the Pleistocene. Its evolutionary relationship to other great ape species, and their divergence during the Middle and Late Miocene (16-5.3 Mya), remains disputed. In part, this is due to the absence of cranial and postcr...
ORGANISM(S): Hominidae 
2019-11-12 | PXD013838 | Pride
Enamel Pleistocene Gigantopithecus Lc-msms 
ProteomicsCOL1 database samples for the Late Pleistocene of Western Eurasia
The project aimed to characterize the collagen type I (COL1) sequences from various modern, Holocene and Pleistocene bone, antler and skin samples for phylogenetic purposes. All extractions were performed at BioArCh, University of York (UK) or the Department of Human Evolution, MPI-EVA (Germany). An...
ORGANISM(S): Ursus americanus (American black bear) (Euarctos americanus) Capreolus capreolus (Roe deer) Aepyceros melampus Vulpes vulpes (Red fox) Crocuta crocuta (Spotted hyena) Castor fiber (Eurasian beaver) Capra ibex (Ibex) Panthera leo (Lion) Cuon alpinus (Dhole) Saiga tatarica (Saiga antelope) Cervus elaphus (Red deer) Gulo gulo (Wolverine) (Gluton) Meles meles (Eurasian badger) Rupicapra rupicapra (Chamois) Lynx lynx (Eurasian lynx) (Felis lynx) Coelodonta antiquitatis (woolly rhinoceros) Alces alces (Eurasian elk) Ursus maritimus (Polar bear) (Thalarctos maritimus) Lutra lutra (European river otter) Vulpes lagopus (Arctic fox) (Alopex lagopus) Martes martes (European pine marten) Axis axis (Axis deer) (Chital) Megaloceros giganteus (Giant deer) (Alces gigantea) Ursus arctos (Brown bear) (Grizzly bear) Rangifer tarandus (Reindeer) (Cervus tarandus) Equus hydruntinus 
2016-09-27 | PXD003190 | Pride
Lc-ms/ms Mammalia Q-exactive hybrid quadrupole-orbitrap ms De novo collagen sequencing 
ProteomicsPalaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne.
The project aimed to characterize the protein composition from 3 Pleistocene bone specimens (AR-7, AR-16, AR-30). Analysed extracts concern standard ZooMS tryptic digests (AR-7, AR-16, AR-30) and additional palaeoproteomic extracts (AR-30A and AR-30B). The latter concern two biological duplicates. A...
ORGANISM(S): Homo 
2016-09-27 | PXD003208 | Pride
Lc-ms/ms Q-exactive hybrid quadrupole-orbitrap ms Homo sp. 
ProteomicsTaxonomic identification of bone fragments in resin-embedded sediment blocks through palaeoproteomics
Identifying the taxonomy of bone fragments in resin-embedded archaeological sediment blocks can provide information about our past at a microstratigraphic resolution. Here, we first explore the effects of resin impregnation on modern bones, and find minimal effects on taxonomic identifications, but ...
ORGANISM(S): Bos taurus (Bovine) Pecora Ursus arctos (Brown bear) (Grizzly bear) Caprinae Canis lupus Ursus Bovinae Equus caballus (Horse) 
2025-09-02 | PXD061447 | Pride
Palaeoproteomics  archaeology  bone  pleistocene  resin 
ProteomicsNam Lot enamel proteome: part of a multi-proxy approach to exploring Homo sapiens arrival, environments and adaptations in Southeast Asia
Here we analyse two enamel protein extractions from a single Late Pleistocene dental fragment from Nam Lot (Laos). The proteome is analyzed for potential phylogenetic information, from which we concude the specimen represents an individual belonging to the genus Pongo, and characterized in terms of ...
ORGANISM(S): Pongo sp. 
2021-11-30 | PXD027426 | Pride
Palaeproteomics Human evolution Enamel Pleistocene Lc-ms/ms 
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