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Proteomicswheat seed phosphoproteome under water deficit
Drought is one of the most serious abiotic stresses, under which the crop yield is significantly reduced. Elite winter wheat cultivar Henong 341 (Triticum aestivum L.) was grown in experimental fields of China Hebei province (116°37′23″E, 37°41′02″N) Two different treatment conditions were designed:...
ORGANISM(S): Triticum aestivum (Wheat) 
2016-07-09 | PXD000806 | Pride
Drought response and defense Phosphoproteome Bread wheat Water stress Seed development 
ProteomicsLC-MS data of IM95 gastric cancer cells following YAP degradation by bioPROTAC
In this study, through naïve nanobody phage library screening, we have identified multiple nanobodies against human YAP with high affinity and specificity. The YAP nanobody was then fused to the RING domain of RNF4, creating a bio-Proteolysis-Targeting Chimera (bioPROTAC) molecule capable of selecti...
ORGANISM(S): Homo sapiens (Human) 
2025-11-03 | PXD063726 | Pride
Gastric cancer cells Yap Bioprotac 
ProteomicsActivation of Akt, Nrf2, and NF-κB signal transduction pathways in the liver as a mechanism of survival for torpid Myotis ricketti Bats
Unfolded protein accumulation in the lumen of endoplasmic reticulum (ER) induced by cold exposure is termed UPRER. Some mammals hibernate to overcome cold winter. We investigated whether hibernating bats are under UPRER and activate Akt, Nrf2, and NF-κB signaling pathways that are critical for cell ...
ORGANISM(S): Myotis ricketti 
2020-11-17 | PXD016109 | Pride
Mitochondria Eif2 Akt Hibernation Upr And lc-ms/ms Nf-κb Bats Proteomics Liver 
MetabolomicsUPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females

Although previous studies have shown that certain factors interfere with the sensitivity of propofol, the mechanisms for interindividual variability in response to propofol remain unclear. This study aimed to screen the metabolites to predict patients' sensitivity to propofol and to identify meta...

2021-09-29 | MTBLS2311 | MetaboLights
UnknownNitrate promotes the growth and the production of short-chain fatty acids and tryptophan from commensal anaerobe <i>Veillonella dispar</i> in the lactate-deficient environment by facilitating the catabolism of glutamate and aspartate.
Not available
S-EPMC11337843 | biostudies-literature
MetabolomicsGallbladder microbial species and host bile acids biosynthesis linked to cholesterol gallstone comparing to pigment individuals

Gallstones are crystalline deposits in the gallbladder that are traditionally classified as cholesterol, pigment or mixed stones based on their composition. Microbiota and host metabolism variances among the different types of gallstones remain largely unclear. Here, the bile and gallstone microb...

2024-03-11 | MTBLS7736 | MetaboLights
UnknownGenome-wide identification of NDR1/HIN1-like genes in kiwifruit and function analysis of AeNHL17 in response to disease resistance.
Not available
S-EPMC11654341 | biostudies-literature
ProteomicsIdentification of Siglec-E-ligand candidates on BCL-1 mouse B cell line by proximity labeling
Siglec-E is a member of Siglec family of glycan recognition proteins involved in the regulation of myeloid cell activities. Siglec-E preferentially recognizes disialic acid, a glycan epitope consisting of two sialic acids conjugated in alpha2-8 linkage (Zhang JQ et al., Eur J Immunol. 2004, 34:1175...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-25 | PXD013032 | Pride
Lc-msms Siglec-e Mouse Ligand B cell Sialic acid 
ProteomicsQuantitative Proteomic Analysis of buffalo ovaries
The ovary is the most important sexual organ of female mammals, and its corpus luteum plays a significant role in mammalian reproduction during the estrus cycle. Here we conducted a quantitative proteomic analysis using tandem mass tag (TMT)-labeling coupled with Nano-LC-MS/MS to explore the mechani...
ORGANISM(S): Bubalus Bubalis 
2019-10-30 | PXD016072 |
ProteomicsQuantitative proteomic atlas of phosphorylation and ubiquitination reveals Epn2-mediated endocytosis dysfunction in α-synuclein transgenic mice
Progression through neuronal loss of substantia nigra pars compacta with Parkinson’s disease depends on various protein post-translational modifications mainly comprising phosphorylation, ubiquitination, acetylation, and methylation. Phosphorylation and ubiquitination regulate major physiological ch...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-28 | PXD013965 | Pride
Phosphorylation Ubiquitination Parkinson’s disease Quantitative proteomics Endocytosis 
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