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ProteomicsA Proteomic Approach to Understanding the Pathogenesis of Idiopathic Macular Hole Formation
Idiopathic macular holes (IMH) are full-thickness defects of retinal tissue that cause severe vision loss due to disruption of the anatomic fovea. Abnormal vitreous traction is involved in the formation of macular holes. Both glial cells and hyalocytes contribute to epiretinal membrane formation in ...
ORGANISM(S): Homo sapiens (Human) 
2018-04-11 | PXD006687 | Pride
Eye Proteomics Vitreous Idiopathic macular hole Retina 
OtherThe proteome of human retina.
Data from ProteomeXchange, PXD ID: PXD001242. File: KYCzx3yI-6939_8.mgf. Published as part of Proteomics. 2014 Nov 19 . From the Abstract: {{i}} The retina is a delicate tissue that detects light, converts photochemical energy into neural signals, and transmits the signals to the visual cortex of t...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320005063 | GPMDB
Resource Reanalysis 
ProteomicsThe proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081766 | MassIVE
ProteomicsPrimary angle closure glaucoma is characterized by altered extracellular matrix homeostasis in the iris
Purpose. To characterize the proteome of the iris in primary angle closure glaucoma (PACG). Experimental Design. In this cross-sectional study, iris samples were obtained from surgical iridectomy of 48 adults with PACG and five normal controls. Peptides from iris were analyzed using liquid chromatog...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD022292 | Pride
Eye Proteomics Primary angle closure glaucoma Iris Extracellular matrix 
ProteomicsThe proteome of normal human retina
The retina is a delicate tissue that detects light, converts photochemical energy into neural signals, and transmits the signals to the visual cortex of the brain. A detailed protein inventory of the proteome of the normal human eye may provide a foundation for new investigations into both the physi...
ORGANISM(S): Homo sapiens (Human) 
2014-11-27 | PXD001242 | Pride
Age-related macular degeneration / eye / human / retina / phototransduction / proteome 
ProteomicsThe proteome of human retrobulbar optic nerve
The optic nerve is a white matter tract that conveys visual information to the brain. A detailed investigation of the proteome of the normal human retrobulbar optic nerve may help facilitate studies of the biology and pathophysiology of the optic nerve. We conducted an in-depth proteomic analysis of...
ORGANISM(S): Homo sapiens (Human) 
2016-08-24 | PXD001581 | Pride
Eye / human / optic nerve / proteome 
ProteomicsThe proteome of normal human sclera
The sclera provides an opaque protective coat for five-sixths of the surface of the human eye. A detailed investigation of the proteome of the normal human sclera may provide insights into the biology and pathophysiology of the sclera. We conducted an in-depth proteomic analysis of sclera from five ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD004223 | Pride
Collagen Proteome Myopia Sclera Eye / human 
ProteomicsThe proteome of normal human sclera
The optic nerve is a white matter tract that conveys visual information to the brain. The sclera comprises the white, protective outer layer of the eye. A characterization of the proteome of normal human retrobulbar optic nerve and sclera may facilitate studies of the eye. We conducted a proteomic a...
ORGANISM(S): Homo sapiens (Human) 
2020-11-24 | PXD022661 | Pride
Human Sclera Proteome 
ProteomicsThe proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...
ORGANISM(S): Homo sapiens (Human) 
2016-02-04 | PXD002194 | Pride
Eye Ciliary body Choroid Iris Retinal pigment epithelium 
ProteomicsThe proteome of human iris - Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. Iris diseases that result in visual disability and blindness include iritis, primary angle closure glaucoma, and pigment dispersion syndrome. A detailed investigation of the proteome of the normal human iris may prov...
ORGANISM(S): Homo sapiens (Human) 
2016-07-18 | PXD001424 | Pride
Iris Proteome Selenoprotein Complement Melanosome Eye 
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