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MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
UnknownGenomic and metabolomic insights into the antimicrobial compounds and plant growth-promoting potential of Bacillus velezensis Q-426.
Not available
S-EPMC10548584 | biostudies-literature
ProteomicsA c-di-AMP receptor mediates epithelial adhesion of Lactiplantibacillus plantarum
Cyclic di-adenosine monophosphate (c-di-AMP) is a crucial second messenger used by bacteria to mediate bacterial-host interactions. However, its roles in Lactiplantibacillus plantarum remain poorly understood. Here, we identify RwpL, which consists solely of an HTH domain, as a c-di-AMP receptor in ...
ORGANISM(S): Lactobacillus plantarum WCFS1 
2026-05-25 | PXD078286 | Pride
Colonization C-di-amp Lactiplantibacillus plantarum 
ProteomicsSOX6 interacting proteins' identification in K562 cells for the regulation of γ-globin gene expression research
Human fetal γ-globin gene is developmentally silenced around the birth, and reactivation of γ-globin gene in adulthood sheds new light on ameliorating symptoms of hemoglobin disorders, such as sickle cell disease (SCD) and β-thalassemias. However, the precise regulation process of γ-globin remains i...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD024259 | Pride
Sox6 K562 Globin Gene expression 
ProteomicsProteomic analysis of cell cycle arrest and differentiation induction caused by ATPR, a derivative of all-trans retinoic acid, in human gastric cancer SGC-7901 cells
Experimental design: Peptides digested from the total cellular proteins were analyzed by reverse phase LC–MS/MS followed by a label-free quantification analysis. The SEQUEST search engine was used to identify proteins and bioinformatics resources were used to investigate the involved pathways for th...
ORGANISM(S): Homo sapiens (Human) 
2017-02-13 | PXD005605 | Pride
Atpr，cell cycle arrest and differentiation，proteomics analysis，pi3k-akt-foxo-p27kip1 pathway，sgc-7901 cells 
Proteomicsrenal cancer cell line ACHN LC-MSMS
To predict the protein that interact with FOXA2 and illustrate the important role and the biological mechanism it may involved of FOXA2 in renal cancer.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD043802 | Pride
Achn Renal cancer Lc-msms 
ProteomicsHuman triple negative breast cancer cell line MDA-MB-231 LC-MSMS
To detect the protein that interact with NONO and illustrate the important role and the biological mechanism it may involved of NONO in TNBC.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051842 | Pride
Tbnc Nono 
UnknownTeriflunomide for multiple sclerosis.
Not available
S-EPMC10493042 | biostudies-literature
UnknownGrid2 interacting protein is a potential biomarker related to immune infiltration in colorectal cancer.
Not available
S-EPMC10644545 | biostudies-literature
TranscriptomicsEffect of GDF11 on RANKL-induced osteoclastogenesis
GDF11 treatment leads to bone loss in mice and strongly stimulates RANKL-induced osteoclastogenesis of bone marrow-“derived macrophages (BMMs) in vitro. We used microarrays to identified distinct classes of up-regulated genes in BMMs after GDF11 treatment. Mouse BMMs were treated with or without GD...
ORGANISM(S): Mus musculus 
2016-07-21 | E-GEOD-84609 | biostudies-arrayexpress
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