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ProteomicsKH_dKO: Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe hypoplasia of skeletal muscles in young mice
Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe hypoplasia of skeletal muscles in young mice
ORGANISM(S): Mus Musculus (mouse) 
2022-11-28 | PXD032244 | JPOST Repository
ProteomicsUnusual cardiac myosin heavy chain post-translational modifications with systolic heart failure
In the present study, we aimed at defining whether cardiac myosin heavy chain (MYH7) post-translational modifications would be altered in systolic heart failure. For that, we had access to septal tissue from donors and from patients with non-genetic dilated cardiomyopathy or with ischemic cardiomyop...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD076695 | Pride
Heart failure  systolic dysfunction  myh7  myosin 
TranscriptomicsRNP immunoprecipitation of fission yeast using Rng3p myosin-specific chaperones to investigate if the association of Rng3p with RNAs occurs on ribosomes
Ribonucleoprotein immunoprecipitation microarray (RIp-chip) study using the Rng3p myosin-specific chaperones from the fission Schizosaccaromyces pombe. Rng3p associates with RNAs encoding myosins. To investigate if the association of Rng3p with these RNAs occurs on ribosomes, Rng3-purified fractio...
ORGANISM(S): Schizosaccharomyces pombe 
2008-12-23 | E-TABM-564 | biostudies-arrayexpress
ProteomicsIdentification of cardiac myosin heavy chain post-translational modifications in hibernating grizzly bears
Mammal hibernation is a physiological process with unclear molecular mechanisms. Here, we aimed to investigate whether cardiac myosin heavy chain post-translational modifications would be affected by hibernation. For that, we used cardiac left ventricle specimens from active and hibernating adult gr...
ORGANISM(S): Ursus arctos (Brown bear) (Grizzly bear) 
2025-05-07 | PXD054499 | Pride
Bear Ptm Myosin 
TranscriptomicsMyosin Heavy Chain-embryonic is a crucial regulator of skeletal muscle development and differentiation.
mRNA from 4 different muscles from control and Myosin heavy chain-embryonic knockout neonate mice were sequenced.
ORGANISM(S): Mus musculus 
2020-03-08 | GSE100331 | GEO
TranscriptomicsRibonucleoprotein immunoprecipitation of fission yeast to study myosin proteins and other cytoskeletal components
Ribonucleoprotein immunoprecipitation microarray (RIp-chip) study using various myosin proteins and other cytoskeletal components from the fission Schizosaccaromyces pombe
ORGANISM(S): Schizosaccharomyces pombe 
2009-09-01 | E-TABM-656 | biostudies-arrayexpress
ProteomicsIdentification of myosin heavy chain post-translational modifications in patients with MHY mutations
Congenital myopathies are rare genetic muscle diseases notably due to mutations in the MYH2 gene. Here we assessed their myosin heavy chain post-translational modifications. For that, we purified beta/slow and type IIa myosin heavy chains from limb muscles of five patients and five healthy controls....
ORGANISM(S): Homo sapiens (Human) 
2023-01-30 | PXD039178 | Pride
Myosin Mhy Ptm 
ProteomicsMyosin Heavy Chain 10 dysregulation in infertile endometrial epithelial cells impairs adhesive capacity
Endometrial receptivity is defined as the functional, morphological, and molecular changes of the endometrium occurring during a limited time period in the menstrual cycle called the ‘window of implantation’. The endometrial luminal epithelial cells are critical in producing this receptivity as thei...
ORGANISM(S): Homo sapiens (Human) 
2026-05-05 | PXD062326 | Pride
Endometrial receptivity Epithelium Endometrial Cell adhesion Actin cytoskeleton Infertility Myh10 Myosin 2 Embryo implantation failure 
ProteomicsCRISPR-Cas9/phosphoproteomics identifies Myosin Light Chain Kinase dependent signaling in kidney epithelial cells
Prior studies have implicated myosin light chain kinase (MLCK) in the regulation of aqua-porin-2 (AQP2) in the renal collecting duct. To discover signaling targets of MLCK, we deleted the Mylk- gene to obtain MLCK-null mpkCCD cells and carried out comprehensive phosphopro-teomics using the SILAC met...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-04 | PXD014985 | Pride
Nuclear membrane Mass spectrometry Vasopressin Aqp2 Endosomal trafficking Sted microscopy 
TranscriptomicsmiR-487b, miR-3963 and miR-6412 delayed myogenic differentiation in C2C12 mouse myoblast-derived cells.
We newly identified skeletal muscle differentiation-associated miRNAs by comparing miRNA expression profile between C2C12 cell and Wnt4-overexpressing C2C12 cell. miR-487b, miR-3963 and miR-6412 are significantly down-regulated in differentiating C2C12 cells, and transfection of their mimics result...
ORGANISM(S): Mus musculus 
2015-11-24 | E-GEOD-63454 | biostudies-arrayexpress
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