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MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Collision Energy Optimization and Fragment Intensity Prediction for Lipid Mediators, Thermo QExactive HF

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1333 | MetaboLights
UnknownCharacterization of different parts of litchi fruit using UHPLC-QExactive Orbitrap.
Not available
S-EPMC9579223 | biostudies-literature
UnknownProtective Mechanism of Polygonum perfoliatum L. Extract on Chronic Alcoholic Liver Injury Based on UHPLC-QExactive Plus Mass Spectrometry Lipidomics and MALDI-TOF/TOF Mass Spectrometry Imaging.
Not available
S-EPMC9179971 | biostudies-literature
ProteomicsData from a proteomic comparative analysis highlight differential adaptation of Lactobacillus delbrueckii subsp. bulgaricus to cow milk versus to soy milk environments
Lactobacillus Bulgaricus (CIRM-BIA1592) adaptation to cow milk versus soymilk environments was studied thanks to proteomics. Bacteria were harvested at the begining of stationary phase. Protein trypsin digestion were performed in solution. The data set contains 22 files of NanoLC-MS/MS analysis, acq...
ORGANISM(S): Lactobacillus delbrueckii subsp. bulgaricus 
2022-08-18 | PXD033905 | Pride
Comparative analysis Adaptation Lactobacillus delbrueckii subsp. bulgaricus Glycine max Soy milk Proteomic Cow milk 
ProteomicsFunctional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.
Allosteric regulation is central to the role of the glycolytic enzyme pyruvate kinase M2 (PKM2) in cancer metabolism. Multiple activating and inhibitory allosteric ligands regulate PKM2 activity by controlling the equilibrium between high activity tetramers and low activity dimers and monomers. Howe...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD010334 | Pride
Srm Prm Pkm2 Quantitation Qexactive 
ProteomicsHaptenation of Macrophage Migration Inhibitory Factor-Dataset 2
Firstly, the adductome of he protein macrophage migration inhibitory factor (MIF) with different haptens encompassing different reaction mechanisms and potencies was investigated. After incubation of MIF with the different haptens at 5 times molar excess of hapten, an untargeted Full MS/dd-MS2 exper...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-18 | PXD031793 | Pride
Pge Dncb Cmit/mit Mif Biomarker Ca 
UnknownDatasets: Sensitivity and protein digestion course of proteomic Filter Aided Sample Preparation.
Not available
S-EPMC6811893 | biostudies-literature
MetabolomicsInositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites
Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of membrane tethers to contact sites between the endoplasmic reticulum (ER) and the plasma membrane is often triggered by calcium. In contrast, we reveal here a funct...
2021-05-06 | MTBLS2444 | MetaboLights
ProteomicsLactobacillus mucosae LM1 and intestinal cell interaction
In this study, we employed a gel-free proteomic approach to investigate proteome changes in both LM1 and IPEC-J2 cells after co-incubation. QExactive Orbitrap mass spectrometry (MS) was used for a full proteomic scan of bacterial and intestinal cells, and for a large-scale quantitative analysis of p...
ORGANISM(S): Lactobacillus mucosae LM1 Sus scrofa domesticus (domestic pig) 
2018-10-24 | PXD006851 | Pride
Host-microbe interaction Label-free proteomics Ipec-j2 Lactobacillus 
ProteomicsHypothalamic protein profiling from mice subjected to social defeat stress
We have analysed changes in the hypothalamus using iTRAQ proteomics 4 plex from mice exposed to social defeat protocol using Qexactive and Orbitrap Velos
ORGANISM(S): Mus musculus (Mouse) 
2024-05-28 | PXD005644 | Pride
Hypothalamus Stress Social defeat 
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