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ProteomicsProteome data of human iPSC and original fibroblast (HDF)
Proteome data for human induced pluripotent stem cells (iPSCs, 201B7) and human dermal fibroblasts (HDFs, HDF1388) were acquired using a Bruker timsTOFpro. These mass spectrometry data were analyzed using DIA-NN 1.8.1.
ORGANISM(S): Homo Sapiens (human) 
2025-04-16 | PXD063003 | JPOST Repository
ProteomicsMoonlighting chaperone 1 activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa
Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa, with the rhl circuit playing the leading role in late and ...
ORGANISM(S): Pseudomonas aeruginosa PA14 
2023-03-11 | PXD038000 | Pride
Rhlr Pseudomonas aeruginosa Pqse Quorum sensing Lc-ms/ms 
ProteomicsCharacterization of the BRD7 and BRD9 homologues - part 1
This submission contains the mass spectrometry files for the manuscript by Lynda Agbo et al. that describes the characterization of mSWI/SNF complexes through functional proteomics analyses. Proteome quantification, AP-MS and proximity biotinylation experiments were performed from Flp-In T-REx HEK29...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-02 | MSV000089357 | MassIVE
ProteomicsCharacterization of the BRD7 and BRD9 homologues - part 2
This submission contains the mass spectrometry files for the manuscript by Lynda Agbo et al. that describes the characterization of mSWI/SNF complexes through functional proteomics analyses. Proteome quantification, AP-MS and proximity biotinylation experiments were performed from Flp-In T-REx HEK29...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-03 | MSV000089362 | MassIVE
ProteomicsMembrane Proteome of Phytophthora parasitica Zoospores: How Does Sensing Occur?
Biflagellated zoospores enable plant pathogens of the Phytophthora genus to locate a host. While rhizospheric signals guiding zoospore movement toward roots are known, their membrane protein composition mediating these responses remains unclear. Here, we use LC-MS/MS to analyze membrane fractions fr...
ORGANISM(S): Phytophthora nicotianae 
2025-06-20 | PXD059087 | Pride
Oomycetes Proteomic Signalling Zoospores Lc-ms Plant physio-pathology 
ProteomicsA cross-disease human microglial framework identifies disease-enriched subsets and tool compounds for microglial polarization.
a. Human microglia play a pivotal role in neurological diseases, but few targeted therapies that directly modulate microglial state or function exist due to an incomplete understanding of microglial heterogeneity. We use single-cell RNA sequencing to profile live human microglia from autopsies or su...
ORGANISM(S): Homo sapiens (Human) 
2025-05-19 | PXD033844 | Pride
A. microglia  single-cell rna sequencing  neurodegeneration  neuroinflammation  disease-associated microglia  alzheimer’s  rnascope-immunofluorescence  microglial model systems  drug targets in neurodegeneration  camptothecin  diapasef  timstofpro 
ProteomicsUnveiling Dopamine and Met-Enkephalin Dynamics: Simultaneous Co-Detection in Rat Striatum
Project description Fast -scan cyclic voltammetry was coupled with carbon microelectrodes for co-detection of dopamine and met-enkephalin at single recording sites in rat striatal slices. The measurements used a specifically designed voltammetric waveform to minimize sensitivity to dopamine, maximiz...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-12-22 | PXD067765 | Pride
Proenkephalin Mass spectrometry Solid-phase extraction Opioid peptide Carbon-fiber microelectrode Fast-scan cyclic voltammetry Mesolimbic pathway 
UnknownQuantitative analysis of proteomic changes in two monoclonal suspension MDCK cell lines infected with human influenza A virus (H1N1).
Not available
S-EPMC12539711 | biostudies-literature
ProteomicsFluvastatin mitigates SARS-CoV-2 infection in human lung cells
Clinical data of patients suffering from COVID-19 have indicated that statin therapy, used to treat hypercholesterolemia, is associated with a better clinical outcome. We therefore investigated the effect of statins on SARS-CoV-2 infection in human lung cells and found that fluvastatin inhibited cor...
ORGANISM(S): Homo sapiens (Human) 
2021-12-07 | PXD023422 | Pride
Hypercholesteremia Sars-cov-2 Risk factor Proteomics Air-liquid-interface culture Cholesterol Virus Fluvastatin Statin Covid-19 
ProteomicsProteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisonsProteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons
Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics and proteomic profiles of plasma-derived large extracellular vesicles (lEVs) in healthy individuals. Twelve partic...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055597 | Pride
Proteomics Fasting Postprandial Extracellular vesicles Plasma Liquid biopsy 
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