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ProteomicsProteomic analysis of the 15k extracellular vesicles from Opisthorchis viverrini
The proteomic content of the extracellular vesicles (EVs) released by the liver fluke Opisthorchis viverrini has been addressed in the past, but they have focused on the small population pelleting at 120k vesicles (also named exosomes). Here we provide the first proteomic analysis of vesicles pellet...
ORGANISM(S): Opisthorchis viverrini 
2024-09-20 | PXD020356 | Pride
Microvesicles Liver fluke Opisthorchis viverrini 15k extracellular vesicles 
ProteomicsProteomic analysis of two populations of Schistosoma mansoni-derived extracellular vesicles: exosome-like vesicles and microvesicles
Extracellular vesicles (EVs) have been characterized from many species of parasitic helminths, and recent experimental evidence supports important functions for their cargo in host-parasite relationships. Here, we carried out a detailed proteomic analysis of two populations of EVs – exosome like ves...
ORGANISM(S): Schistosoma mansoni (Blood fluke) 
2019-10-17 | PXD015857 | Pride
Schistosoma mansoni Proteomics Exosome-like vesicles Microvesicles Extracellular vesicles 
ProteomicsUterine extracellular vesicles in the mare.
The protein cargos of uterine extracellular vesicles isolated from uterine lavages, collected from pregnant mares (P; day 10, 11, 12 and 13 after insemination) and cyclic control mares (C; day 10 and 13 after insemination), was analyzed.
ORGANISM(S): Equus caballus (Horse) 
2022-10-15 | PXD032405 | Pride
Equus caballus Pregancy Uterine extracellular vesicles 
ProteomicsDiversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
Advances in understanding intercellular communication through extracellular vesicles (EVs) and non-vesicular extracellular nanoparticles (NVEPs) have been limited by their cellular heterogeneity and unclear origins. Using sequential ultracentrifugation, we identified high- and low-density EVs and pe...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD059671 | Pride
Supermeres Extracellular nanoparticles Exomeres Extracellular vesicles Glioblastoma Egfr 
ProteomicsCirculating tumour cells shed large extracellular vesicles in capillary-scale bifurcations
Data Independant Acquisition (DIA)-based proteomics to characaterise the proteins identified in Large Extracellular vesicles (LEVs) samples.
ORGANISM(S): Homo sapiens (Human) 
2025-09-01 | PXD050444 | Pride
Large extracellular vesicles 
ProteomicsPROTEOLYTIC ACTIVITIES OF EXTRACELLULAR VESICLES ATTENUATE A-SYNUCLEIN AGGREGATION AND MODULATE ITS TOXICITY
Extracellular vesicles (EVs) are nano-sized lipid vesicles released from cells into the extracellular milieu. We examined the yet unexplored role(s) of EVs in α-synuclein (α-syn) degradation and recipient-cell homeostasis, and whether EVs can affect the processing of extracellular α-syn species, the...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-06 | PXD044320 | Pride
Proteomics A-synuclein Extracellular vesicles Proteases 
ProteomicsThe surface proteome of extracellular vesicles from Fasciola hepatica
Helminth parasites secrete extracellular vesicles (EVs) as a means of exporting effector molecules into the host microenvironment. Once released, the parasite-derived EVs are internalised by host immune cells and trigger a range of biological effects including modulation of host immunity. While the ...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2019-11-12 | PXD007782 | Pride
Fasciola hepatica Exosome Extracellular vesicle 
ProteomicsProteomic profiling of glioblastoma stem cells and their small extracellular vesicles
The heterogeneous nature of glioblastoma stem-like cells (GSCs) creates hurdles in developing effective therapies against glioblastoma, making it extremely difficult to eradicate. In this part of the project, we investigated the potential role of GSCs-derived small extracellular vesicles (sEVs) in g...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD036359 | Pride
Glioblastoma Glioblastoma stem cells Exosomes Tumor heterogeneity Proteomics Small extracellular vesicles 
ProteomicsA novel method for isolation of spontaneously-released brain small extracellular vesicles
Extracellular vesicles (EVs), including small EVs (sEVs) such as exosomes, exhibit great potential for the diagnosis and treatment of brain disorders, representing an advantageous tool for Precision medicine. The latter demands high-quality human biospecimens, especially in complex disorders in whic...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031947 | Pride
Exosomes Extracellular vesicles Brain Human Spontaneous release Mouse 
UnknownSurface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells.
Not available
S-EPMC6355031 | biostudies-literature
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