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ProteomicsProbing the complementarity of FAIMS and strong cation exchange chromatography in shotgun proteomics
This dataset contains the raw data from the JASMS paper with the same title and DOI: 10.1007/s13361-012-0544-2. We compared the results of shotgun proteomic experiments of a trypsin digest of SUM52 cell lysate using 2D-LC fractionated (strong cation exchange and reversed phase of 6 SCX fractions) w...
ORGANISM(S): Homo sapiens (Human) 
2013-12-05 | PXD000596 | Pride
Cid Scx Etd Sum52 Faims 
ProteomicsQualitative Analysis of short open reading frame encoded proteins from Methanosarcina mazei under stress conditions via bottom up and top down proteomics
In the present work we have analysed Methanosarcina mazei grown under different stressor conditions via combined top-down and bottom-up proteomic workflows to determine which SEP are differenitally present in responce to stress conditions
ORGANISM(S): Methanosarcina mazei Go1 
2024-09-24 | PXD055745 | Pride
Top-down proteomics Proteoforms Methanosarcina mazei 2d-lc-faims-ms/ms Bottom-up proteomics 
ProteomicsAccurate quantitative proteomic analyses using metabolic labeling and High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS)
Stable isotope labeling by amino acids in cell culture (SILAC) is routinely used to profile changes in protein and peptide abundance across different experimental paradigms. As with other quantitative proteomic approaches, the detection of peptide isotopomers can be limited by the presence of interf...
ORGANISM(S): Homo sapiens (Human) 
2019-05-28 | PXD012924 | Pride
Phosphorylation High field asymmetric waveform ion mobility spectrometry (faims) Stable isotope labeling by amino acids in culture (silac) Quantitative proteomics 
ProteomicsDetermination of the peroxisome proteome of pathogenic stage Histoplasma capsulatum via Proximity Labeling
During infection, Histoplasma capsulatum exists primarily as an intracellular pathogen of phagocytes where it overcomes host defense mechanisms and replicates in the phagosome. This intracellular proliferation of Histoplasma yeasts requires the function of the fungal peroxisome for multiple, incompl...
ORGANISM(S): Histoplasma ohiense 
2026-06-04 | PXD076035 | Pride
Histoplasma Proximity labeling Fungi Peroxisomes 
ProteomicsCancer Mutations Rewire the RNA Methylation Specificity of METTL3-METTL14
Chemical modification of RNAs is important for post-transcriptional gene regulation. The METTL3-METTL14 complex generates most N6-methyladenosine (m6A) modifications in mRNAs, and dysregulated methyltransferase expression has been linked to numerous cancers. Here we show that m6A modification locati...
ORGANISM(S): Homo sapiens (Human) 
2024-12-21 | PXD039447 | Pride
Oncogenesis Mettl3 M6a Mettl14 Lc-ms/ms Hepg2 
ProteomicsIdentification of Bifidobacterium longum subsp. infantis ATCC 15697 surface proteins after growth in milk phospholipid-enriched medium
Bifidobacterium infantis is associated with the gut microbiota of breast-fed infants. B. infantis promotes intestinal barrier and immune function through several proposed mechanisms, including interactions between their surface polysaccharides, the host, and other gut microorganisms. Dairy foods and...
ORGANISM(S): Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) 
2023-05-15 | PXD042186 | Pride
Milk phospholipids Surface proteins Bifidobacteria 
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