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TranscriptomicsStrand-specific RNA-seq reveals ordered patterns of sense and antisense transcription in Bacillus anthracis
Although genome-wide transcriptional analysis has been used for many years to study bacterial gene expression, many aspects of the bacterial transcriptome remain undefined. A prominent example is antisense transcription, which has been observed in a number of bacteria, though the function of antise...
ORGANISM(S): Bacillus anthracis 
2012-03-15 | E-GEOD-36506 | biostudies-arrayexpress
TranscriptomicsRho and NusG suppress pervasive antisense transcription in Escherichia coli [RNA-seq].
Despite the prevalence of antisense transcripts in bacterial transcriptomes, little is known about how their synthesis is controlled. We report that a major function of the Escherichia coli termination factor Rho and its co-factor NusG is suppression of ubiquitous antisense transcription genome-wide...
ORGANISM(S): Escherichia coli K-12 
2012-11-01 | E-GEOD-41939 | biostudies-arrayexpress
ProteomicsRNA antisnse puriification of Tau exon 10 pre-mRNA
In this study, we demonstrated the use of the RNA Antisense Purification by Mass Spectrometry (RAP-MS) method to identify proteins involved in specific alternative splicing events. Specifically, we applied the RAP-MS method to identify proteins that interact with the Tau pre-mRNA around its exon 10 ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023523 | Pride
Tau Splicing Human Rna antisense purification Rap-ms 
TranscriptomicsThe effect of temperature on Natural Antisense Transcript (NAT) expression in Aspergillus flavus
Naturally occurring Antisense Transcripts (NATs) compose an emerging group of regulatory RNAs. These regulatory elements appear in all organisms examined, but little is known about global expression of NATs in fungi. Analysis of currently available EST sequences suggests that 352 cis NATs are pres...
ORGANISM(S): Aspergillus flavus 
2010-06-21 | E-GEOD-12594 | biostudies-arrayexpress
TranscriptomicsEffects of AβPP Antisense Treatment on Hippocampal Gene Expression in Adult Mice with Memory Deficits
The purpose of this study was to determine the effect of peripheral (IV) administration of AβPP antisense on hippocampal gene expression as well as on learning and memory as measured by T-maze in adult male mice aged 12 months. The AβPP antisense treatment reversed learning and memory deficits and ...
ORGANISM(S): Mus musculus 
2015-02-13 | E-GEOD-65877 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of expression and DNA methylation at CpG-island-associated sense-antisense transcript loci in mouse
Sense-antisense transcript (SAT) pairs are pairs of transcripts that fully or partially overlap but are transcribed in opposite directions. Although SAT expression occurs in various species, most SAT pairs have not been examined in detail. Because our previous studies revealed some tissue specificit...
ORGANISM(S): Mus musculus 
2010-08-26 | E-GEOD-14392 | biostudies-arrayexpress
ProteomicstRF-24 RNA pulldown in KYSE150 and KYSE30
To delineate the oncogenic mechanism of tRF-24 in ESCC, we performed RNA pull-down assays with biotinylated tRF-24 and antisense control, followed by mass spectrometry (MS) analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD063163 | Pride
Human Kyse30 Esophagus Rna-pulldown Kyse150 
TranscriptomicsSpt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast [RNA-seq]
Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain a comprehensive understanding of the requirements for this critical factor, we have performed genome-wide analyses of transcription, chromatin structure...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-09 | E-GEOD-49573 | biostudies-arrayexpress
ProteomicsLETR1 (LINC01197) RNA pull-down in human LECs followed by LC-MSMS
Recent studies have revealed the importance of long noncoding RNAs (lncRNAs) as tissue-specific regulators of gene expression. There is ample evidence that distinct types of vasculature undergo tight transcriptional control to preserve their structure, identity, and functions. We determined, for the...
ORGANISM(S): Homo sapiens (Human) 
2020-12-21 | PXD018578 | Pride
Human Lesr2 Lc-msms Linc01197 Lncrna Lecs 
TranscriptomicsAntisense Expression of Annotated Genes
Contains a row for each annotated gene in each sample, indicating whether our analysis called the region antisense to the coding region of the gene "present" or "absent" in the sample. Gene names and coordinates refer to version 3 of the TIGR annotation as submitted to GenBank (GI numbers 22330780, ...
ORGANISM(S): Arabidopsis thaliana 
2010-06-05 | E-GEOD-637 | biostudies-arrayexpress
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