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ProteomicsAdvancing Understanding of the Protein Composition of Human Seminal Extracellular Vesicles
Seminal extracellular vesicles (SEVs) carry a diverse array of bioactive molecules, including proteins, lipids, and nucleic acids, which influence sperm function and have potential to modulate the female reproductive tract immune response after intromission. However, the full spectrum of SEV cargo i...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-15 | PXD047212 | Pride
ProteomicsElucidation of the protein composition of mouse seminal vesicle fluid
The seminal vesicles are male accessory sex glands that contribute the bulk of the seminal plasma in which mammalian spermatozoa are bathed during ejaculation. In addition to helping convey sperm through the ejaculatory duct, seminal vesicle secretions support sperm survival after ejaculation and in...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-20 | PXD028564 | Pride
Proteomics Bioinformatics Seminal vesicle fluid 
ProteomicsImmortalized mouse caput epididymal (mECap18) cell line recapitulates in vivo environment
Between the testes and the vas deferens lies the epididymis, a highly convoluted tubule whose unique environmental characteristics are crucial for the functional maturation of spermatozoa. Within the epididymal epithelium, the secretory system releases small non-coding RNA molecules (sncRNAs) and pr...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-29 | PXD042082 | Pride
Fertility Epididymis Male reproduction Sperm maturation Proteomics. 
UnknownRationally Engineered Tandem Facial Amphiphiles for Improved Membrane Protein Stabilization Efficacy.
Not available
S-EPMC7233144 | biostudies-literature
UnknownThe prevalence of subthreshold psychiatric symptoms and associations with alcohol and substance use disorders: from a nationally representative survey of 36,309 adults.
Not available
S-EPMC9012038 | biostudies-literature
TranscriptomicsThe alternative complement pathway appears to be a UVA sensor that leads to systemic immunosuppression
Ultraviolet (UV) wavebands in sunlight are immunomodulatory. About half the amount of UVA within a minimum erythemal dose of sunlight is systemically immunosuppressive, while higher doses protect from UVB immunosuppression in mice. We have previously shown that these responses to UVA are genetically...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15618 | biostudies-arrayexpress
UnknownCell proliferation within small intestinal crypts is the principal driving force for cell migration on villi.
Not available
S-EPMC5241155 | biostudies-literature
ProteomicsIdentifying a novel hydroxysteroid dehydrogenase enzyme that is capable of testosterone biosynthesis in the mouse
Androgens, such as testosterone and dihydrotestosterone (DHT), are essential for male sexual development, masculinisation, spermatogenesis, and general lifelong health. Androgens are predominantly synthesised in the testes of mice (~95%) by highly specialised cells known as the Leydig cells. There a...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-12 | PXD050748 | Pride
Androgens Alternate pathway Hsd17b7 Canonical pathway Testosterone Srd5a1 Testosterone biosynthesis Hsd17b3 
TranscriptomicsAplysia pleural Ganglia 1 Hour After Long-Term Sensitization Training
We used a custom-designed microarray and qPCR to characterize the rapid transcriptional response to long-term sensitization training in the marine mollusk Aplysia californica. Aplysia were exposed to repeated noxious shocks to one side of the body (4 ten-second shocks at 90mA, 30 min ISI), a proced...
ORGANISM(S): Aplysia californica 
2014-05-08 | E-GEOD-57458 | biostudies-arrayexpress
ProteomicsGlobal profiling of the proteomic changes associated with the post-testicular maturation of mouse spermatozoa
Spermatozoa acquire fertilization potential during passage through a highly specialized region of the extra-testicular ductal system known as the epididymis. In the absence of de novo gene transcription or protein translation, this functional transformation is extrinsically driven via the exchange o...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-21 | PXD028834 | Pride
Rhoa Proteomics Mass spectrometry Acrosome reaction Sperm maturation Epididymis Male fertility Sperm proteome Spermatozoa 
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