Sort   by:  
 Page size 
UnknownIdentification of a Potential Founder Effect of a Novel PDZD7 Variant Involved in Moderate-to-Severe Sensorineural Hearing Loss in Koreans.
Not available
S-EPMC6747409 | biostudies-literature
UnknownInfluence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer.
Not available
S-EPMC4541384 | biostudies-literature
ProteomicsPeptidylarginine deiminase 2 (PADI2) is a key regulator for osteoblast differentiation and bone formation through the maintenance of citrullination-mediated RUNX2 stability
Peptidylarginine deiminase (PADI) 2 catalyzes the posttranslational conversion of peptidyl-arginine to peptidyl-citrulline, a process called citrullination. However, the exact function of PADI2 in bone development and bone homeostasis remains unknown. In this study, we found that Padi2 deficiency le...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD040179 | Pride
Citrullination Ptm Padi2 Lc-msms Runx2 
ProteomicsNSMF promotes the replication stress-induced DNA damage response for genome maintenance
Proper activation of DNA repair pathways in response to DNA replication stress is critical for maintaining genomic integrity. Due to the complex nature of the replication fork (RF), problems at the RF require multiple proteins, which remain unidentified, for resolution. In this study, we identified ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021942 | Pride
Atr Cdc5l Rpa2 Replication fork Lc-ms/ms 
ProteomicsOxygen-confined photooxidation represents a novel form of oxidative protein damage
Oxidative modifications can disrupt protein folds and functions, and are strongly associated with human aging and diseases. Conventional oxidation pathways typically involve the free diffusion of reactive oxygen species (ROS), which primarily attack the protein surface. Yet, it remains unclear wheth...
ORGANISM(S): Homo Sapiens (human) Escherichia Coli 
2024-11-27 | PXD056895 | JPOST Repository
TranscriptomicsSTAT3-mediated CD133 upregulation promotes hepatocellular carcinoma
We identified a novel mechanism by which IL-6/STAT3 signaling up-regulates CD133 expression and promotes HCC progression. STAT3 activation upregulates the expression of CD133 during liver carcinogenesis. Targeting STAT3-mediated CD133 overexpression may represent a promising therapeutic strategy for...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-60194 | biostudies-arrayexpress
Sort   by:  
 Page size