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TranscriptomicsBronchiolar progenitors and club cells in mouse lung
Gene expression patterns of bronchiolar progenitors and club cells in mouse lung were examined by microarray experiments. Although it has not yet been fully characterized, a subset of epithelial cells lining bronchioles are best understood as bronchiolar progenitors that self-renew over the long ter...
ORGANISM(S): Mus musculus 
2016-02-17 | E-MTAB-4460 | biostudies-arrayexpress
UnknownClub Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics.
Not available
S-EPMC10472444 | biostudies-literature
GenomicsPulmonary fibrosis after COVID-19 is characterized by airway abnormalities and elevated club cell secretory protein-16
Pulmonary fibrosis after COVID-19 is characterized by airway abnormalities and elevated club cell secretory protein-16
PRJNA1331709 | ENA
UnknownProtective role for club cell secretory protein-16 (CC16) in the development of COPD.
Not available
S-EPMC4451404 | biostudies-literature
UnknownClub Cell Secretory Protein Deficiency Leads to Altered Lung Function.
Not available
S-EPMC6363971 | biostudies-literature
UnknownClub cell secretory protein (CC16) polymorphisms in preterm neonates with respiratory distress syndrome and bronchopulmonary dysplasia.
Not available
S-EPMC12081523 | biostudies-literature
ProteomicsAblation or Inhibition of Protein Disulfide Isomerase A3 (PDIA3) in Aberrant Club Cells Attenuates Osteopontin (SPP1) Production and Pulmonary Fibrosis
Rationale: The role of club cells in the pathology of Idiopathic Pulmonary Fibrosis IPF is not well understood. PDIA3, an endoplasmic reticulum (ER) based redox chaperone catalyzes the cysteine disulfide bonds (-S-S-) in various fibrosis-related proteins; however, mechanisms of action of PDIA3 in pu...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-11 | PXD021715 | Pride
Ipf Pdia3 Osteopontin Upr Pulmonary fibrosis Loc14 Spectral counting Ccsp Lc-ms/ms 
TranscriptomicsClara cell regulation of the inflammatory response
Chronic lung diseases are marked by excessive inflammation and epithelial remodeling. Reduced Clara cell secretory function and corresponding decreases in the abundance of the major Clara cell secreted protein, CCSP, are characteristically seen in these disease states. We sought to define the impact...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-16409 | biostudies-arrayexpress
UnknownPlasma club cell secretory protein reflects early lung injury: comprehensive epidemiological evidence.
Not available
S-EPMC12006028 | biostudies-literature
UnknownSurfactant Protein D and Club Cell Secretory Protein as Biomarkers of Disease Severity and Fostamatinib Efficacy in Severe COVID-19.
Not available
S-EPMC12020689 | biostudies-literature
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