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ProteomicsProfiling protein kinases and other ATP binding proteins in Arabidopsis using acyl-ATP probes
Many protein activities are driven by ATP binding and hydrolysis. Here, we explore the ATP binding proteome of the model plant Arabidopsis thaliana using Acyl-ATP (AcATP) probes. These probes target ATP binding sites and covalently label lysine residues in the ATP binding pocket. Protein extracts we...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2013-06-19 | PXD000188 | Pride
Abpp Lc-msms Kinases Activity-based protein profiling Arabidopsis 
ProteomicsStructural basis for the inhibition of pathogenic serine ubiquitination by the Legionella metaeffector SidJ
Structural and functional studies of SidE-family effectors and the metaeffector SidJ in the infection mechanism of Legionella pneumophila, elucidating the role of post-translational modification in modulating effector toxicity.
ORGANISM(S): Legionella pneumophila 
2021-09-20 | PXD028638 | Pride
Serine ubiquitination Autoampylation Legionella Glutamylation Adp-ribosylation Adenylation Ubiquitin 
ProteomicsHistone ADP Ribosylation - Serine is a new target residue for endogenous ADP-ribosylation on histones
ADPr sites on histones obtained from cells were directly identified. We have identified 12 unique ADPr sites in human osteosarcoma cells and report serine ADPr as a new type of histone mark that responds to DNA damage.
ORGANISM(S): Homo sapiens (Human) Gallus gallus (Chicken) 
2016-12-22 | PXD005462 | Pride
Adpr Histones Serine Adp ribosylation 
ProteomicsIdentification of mono-ADPr readers by multilevel chromatin proteomics
We performed multilevel proteomics to identify mono-ADPr readers. Pulldowns using ADPribosylated peptides and nucleosomes, analysis of the chromatin proteome using targeted modulations of the ADPr system (H2O2 treatment, ARH3 KO, HPF1 KO). We reveal multiple mono-ADPr readers, including RNF114, a ...
ORGANISM(S): Homo sapiens (Human) 
2023-04-28 | PXD037026 | Pride
Adpribosylation Histone marks Human Ptm Mono-adpr Chromatin Lc-ms/ms 
UnknownLong-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Not available
S-EPMC9471490 | biostudies-literature
UnknownProcessing of protein ADP-ribosylation by Nudix hydrolases.
Not available
S-EPMC6057610 | biostudies-literature
UnknownAcute HIV-1 infection viremia associate with rebound upon treatment interruption.
Not available
S-EPMC9464709 | biostudies-literature
UnknownProspective study on embolization of intracranial aneurysms with the pipeline device (PREMIER study): 3-year results with the application of a flow diverter specific occlusion classification.
Not available
S-EPMC9985759 | biostudies-literature
UnknownProspective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results.
Not available
S-EPMC6996098 | biostudies-literature
UnknownDe Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures.
Not available
S-EPMC6037130 | biostudies-literature
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