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UnknownExistential threat and responses to emotional displays of ingroup and outgroup members
Not available
S-EPMC10665133 | biostudies-literature
ProteomicsGenomic and Secretomic analysis of Blastobotrys yeasts reveal key xylanases for biomass decomposition
Xylanolytic enzyme systems in ascomycetous yeasts remain underexplored, despite the presence of yeasts in various xylan-rich ecological niches. In this study, we investigated the secreted xylanolytic machineries of three Blastobotrys species—B. mokoenaii, B. illinoisensis, and B. malaysiensis—by int...
ORGANISM(S): Blastobotrys 
2025-08-25 | PXD061695 | Pride
Gh11 Xylan Gh30 Xylanolytic yeast 
UnknownRing Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.
Not available
S-EPMC4976663 | biostudies-literature
ProteomicsCytoskeleton-associated protein 4 (CKAP4) affects podocyte cytoskeleton dynamics in diabetic kidney disease.
Cytoskeleton-associated protein 4 (CKAP4) stabilizes the endoplasmic reticulum, by regulating its folding and anchoring to the microtubular cytoskeleton. Since podocytes are highly dependent on an intact cytoskeleton to exert their function, the role of CKAP4 was explored during normal conditions an...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD046643 | Pride
Cytoskeleton Diabetic kidney disease Integrins Podocytes Microtubules Ckap4 
ProteomicsCharacterization of MdpS: An In-depth Analysis of a MUC5B-Degrading Protease from Streptococcus oralis
Oral biofilms, comprising hundreds of bacteria and other microorganisms on oral mucosal and dental surfaces, play a central role in oral health and disease dynamics. Streptococcus oralis, a key constituent of these biofilms, contribute significantly to their formation, serving as an early colonizer ...
ORGANISM(S): Homo sapiens (Human) 
2024-04-18 | PXD046810 | Pride
Serine protease O-glycosylation Mucin degradation Oral biofilm Muc5b Streptococcus oralis 
UnknownOne in three adenomas could be missed by white-light colonoscopy - findings from a systematic review and meta-analysis.
Not available
S-EPMC11908064 | biostudies-literature
ProteomicsGlycoproteomic and phenotypic elucidation of B4GALNT2 expression variants in the SID histo-blood group system
The Sda histo-blood group antigen [GalNAcβ1-4(NeuAcα2-3)Galβ-R] is present in colon, kidney and body fluids among 96-98% of Europeans whilst 90% have Sda-positive erythrocytes. Sda is implicated in various infections and constitutes a potential biomarker for colon cancer. The 2-4% truly Sd(a‒) indiv...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD023943 | Pride
Glycosylation Flow cytometry Glycopeptide Glycobiology Glycoprotein Sid blood group system Carbohydrate biosynthesis Erythrocyte Gene expression Glycosyltransferase 
UnknownA computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes.
Not available
S-EPMC6001404 | biostudies-literature
ProteomicsN-glycoproteomic analyses of human intestinal enteroids, varying in histo-blood group geno- and phenotypes, reveal a wide repertoire of fucosylated glycoproteins
Human noroviruses, globally the main cause of viral gastroenteritis, show strain specific affinity for histo-blood group antigens (HBGA) and can successfully be propagated ex vivo in human intestinal enteroids (HIEs). HIEs established from jejunal stem cells of individuals with different ABO, Lewis ...
ORGANISM(S): Homo sapiens (Human) 
2024-04-10 | PXD046494 | Pride
Higher-energy collision dissociation Intestinal epithelium : glycoproteomics Host-pathogen interaction Histo-blood group antigens Human intestinal enteroids Fucosyltransferase Human norovirus Lc-ms/ms 
ProteomicsGlycosylation of somatic extracts and secretome in the infective stage of the helminth Fasciola hepatica
Fasciola hepatica is a global helminth parasite of humans and their livestock. The invasive stage of the parasite, the newly excysted juvenile (NEJs), relies on glycosylated excretedsecreted (ES) products and surface/somatic molecules to interact with host cells and tissues and to evade the host's i...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2024-01-26 | PXD045488 | Pride
Glycoproteomics Orbitrap Parasites Glycosylation Lc-ms/ms 
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