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TranscriptomicsTranscription profiling of human 27 non-labored normal preterm and 9 non-labored normal term basal plate samples to investigate gene expression at the human maternal-fetal interface
Microarray analysis to globally assess gene expression at the maternal-fetal interface Experiment Overall Design: 27 non-labored normal preterm and 9 non-labored normal term basal plate samples were analyzed on Affymetrix U133 chips using established protocols. The gene expression profile of prete...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-5999 | biostudies-arrayexpress
MetabolomicsHeadspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS
Ventilator-associated pneumonia (VAP) is a healthcare-acquired infection arising from the invasion of the lower respiratory tract by opportunistic pathogens in ventilated patients. The current method of diagnosis requires the culture of an airway sample such as bronchoalveolar lavage, which is invas...
2018-08-08 | MTBLS497 | MetaboLights
ProteomicsAn integrated omics approach reveals synaptic plasticity changes in an APP/PS1 Alzheimer´s mouse model
Synaptic dysfunction occurs early in Alzheimer´s disease. However, efforts to protect against these detriments have not been possible due to the inadequate understanding of synaptic signalling pathways involved in the neuropathological disease process. The aim of this study was to elucidate the mole...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-11 | PXD003312 | Pride
Cortex Synapse Neuroinflammation Tau protein Proteomics Hippocampus Mirna Amyloid Olfactory bulb Dendritic spine Brainstem 
MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
ProteomicsRuegeria pomeroyi on R/S DHPS and L-Cys compared to glucose
This project invovles the identification of the pathways responsible for the breakdown of different Sulfur containing biomolecules including R/S DHPS and L-Cys compared to glucose
ORGANISM(S): Ruegeria pomeroyi DSS-3 
2026-06-20 | PXD069364 | Pride
Ruegeria pomeroyi 
UnknownGene expression polymorphism underpins evasion of host immunity in an asexual lineage of the Irish potato famine pathogen.
Not available
S-EPMC6032779 | biostudies-literature
ProteomicsEstablishment of fetomaternal tolerance via glycan-mediated B cell suppression
The immune system must be able to distinguish self from non-self. During pregnancy, the mother’s immune system does not recognize the placenta as foreign because proteins expressed by tropbholasts, the placental cells that interface with the maternal immune system, do not activate maternal T cells. ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-01-12 | PXD029966 | Pride
Lc-msms Cd22 Placenta glycoproteins Sialic acid Fetomaternal tolerance B cells 
MetabolomicsPronounced uptake and metabolism of organic substrates by diatoms revealed by pulse-labeling metabolomics
Diatoms contribute as a major group of microalgae to approximately 20% of the global carbon fixation. In the plankton, these algae are exposed to a plethora of metabolites, especially when competing algae are lysed. In line with evidence that these phototrophs can also engage in heterotrophy we aske...
2021-12-09 | MTBLS2333 | MetaboLights
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
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