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TranscriptomicsTranscriptome Sequencing During Mouse Brain Development Identifies Long Non-Coding RNAs Functionally Involved in Neurogenic Commitment
Transcriptome analysis of somatic stem cells and their progeny is fundamental to identify new factors controlling proliferation versus differentiation during tissue formation. Here we generated a combinatorial, fluorescent reporter mouse line to isolate proliferating neural stem cells, differentiati...
ORGANISM(S): Mus musculus 
2013-11-18 | E-GEOD-51606 | biostudies-arrayexpress
UnknownArtificial intelligence applied to 'omics data in liver disease: towards a personalised approach for diagnosis, prognosis and treatment.
Not available
S-EPMC11874365 | biostudies-literature
UnknownCobalt(III) Werner Complexes with 1,2-Diphenylethylenediamine Ligands: Readily Available, Inexpensive, and Modular Chiral Hydrogen Bond Donor Catalysts for Enantioselective Organic Synthesis.
Not available
S-EPMC4827665 | biostudies-literature
ProteomicsThe impact of biomaterial cell contact on the immunopeptidome
Biomaterials play an increasing role in clinical applications and regenerative medicine. Modern biomaterials should imitate the function of damaged tissue without triggering an immune response, initiate self-regeneration of the body and gradually degrade after implantation. The immune system is now ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-01 | PXD019258 | Pride
Monocytes Foreign body response Biocompatibility Mass spectrometry Immunopeptidomics Host response Biocompatibility assay Biomaterials 
ProteomicsValidation of a high-performance liquid chromatography-tandem mass spectrometry immunopeptidomics assay for the identification of HLA ligands suitable for pharmaceutical therapies
For more than two decades naturally presented, human leukocyte antigen (HLA)-restricted peptides (immunopeptidome) have been eluted and sequenced using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Since, identified disease-associated HLA ligands have been characterized and evaluated as...
ORGANISM(S): Homo sapiens (Human) 
2020-01-15 | PXD012797 | Pride
Validation Mass spectrometry Gmp Cancer immunotherapy Immunopeptidome Lc–ms/ms 
ProteomicsIdentification of changes in the LNZ308 HLA immunopeptidome after virotherapy, irradiation and chemotherapy
Glioblastoma is an aggressive incurable primary malignant brain tumor. Measles virus (MeV) therapy is a promising upcoming treatment strategy with proven preclinical efficacy and clinical safety. Using RNA Sequencing and immunopeptidome analyses, we aimed at identifying a synergistic combination reg...
ORGANISM(S): Homo sapiens (Human) 
2018-02-19 | PXD008984 | Pride
Human Oncolytic virotherapy Glioblastoma Lcms Personalized immunotherapy Immunopeptidome 
ProteomicsUnveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices
The classical HLA-C and the nonclassical HLA-E and HLA-G molecules play important roles both in the innate and adaptive immune system. Starting already during embryogenesis and continuing throughout our lives, these three Ags exert major functions in immune tolerance, defense against infections, and...
ORGANISM(S): Homo sapiens (Human) 
2018-04-20 | PXD009531 | Pride
Hla-e Hla-g Binding prediction  peptide motifs Hla-c Lc-msms 
ProteomicsChicken MHC class II presented Marek's disease virus (MDV) and infectious bursal disease virus (IBDV) antigenic peptides
Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to zoonotic pathogens. Unlike humans and other typical mammals, the major histocompatibility complex (MHC) of chickens can confer...
ORGANISM(S): Gallus gallus (Chicken) 
2021-09-10 | PXD023954 | Pride
Mdv Chicken mhc Immunopeptidomics Mhc class ii Ibdv Mhc class i 
UnknownThe Women's Health Initiative: The food environment, neighborhood socioeconomic status, BMI, and blood pressure.
Not available
S-EPMC4018819 | biostudies-literature
UnknownExposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review.
Not available
S-EPMC8739508 | biostudies-literature
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