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ProteomicsBreast tissue and cancer proteomics
Breast tissue sample from the Koman tissue bank and UW Oncology. Proteomic analysis of non-cancer tissue by BMI catagory.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051458 | Pride
Breast cancer Bmi Tumor Extracellular matirx 
ProteomicsCOVIDomics_plasma_2020_DDA-PASEF
In order to investigate variations in the endotype of COVID19 patients, we completed an integrated analysis of 112 research participants, including 74 COVID19 patients versus 37 SARS-CoV-2 negative controls. COVID19 patients tested positive for SARS-CoV-2 infection by PCR and/or antibody testing and...
ORGANISM(S): Homo sapiens (Human) 
2021-03-04 | PXD022817 | Pride
Multi-omics Plasma Covid-19 
ProteomicsTargeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
Analysis of bone marrow stroma and MVNs via LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012002 | Pride
Ecm Tumour dormancy Perivascular niche Theraputic resistance Extracellular matrix 
ProteomicsLysyl Oxidase Mediated Collagen Cross-linking in Pancreatic Cancer
Bottom up proteomics, cross-linked amino acid analysis, and cross-linked peptide analysis were performed on eight PDAC tumor samples and paired adjacent non-tumor samples.
ORGANISM(S): Homo sapiens (Human) 
2025-08-28 | PXD050833 | Pride
Collagen Lysyl hydroxylase Xaaa Lysyl oxidase N-telo peptide Plod Lox Cross-linked peptide Ntx Pdac 
ProteomicsFine mapping of the pulmonary artery matrisome in a large animal model of hypoxia-induced pulmonary hypertension
Pulmonary hypertension (PH) is a progressive disease with a high mortality rate, usually as a result of right heart failure. The pulmonary vasculature in PH is characterized by remodeling and stiffening, potentially with luminal obstruction, driven by enhanced cell proliferation/survival versus cell...
ORGANISM(S): Bos taurus (Bovine) 
2025-12-08 | PXD046794 | Pride
Intravascular fibrin Proteomics Intima Pulmonary artery Matrisome Fibrosis Pulmonary hypertension Extracellular matrix Blood vessel wall 
ProteomicsHydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization
The extracellular matrix (ECM) is readily enriched by decellularizing tissues with non-denaturing detergents to solubilize and deplete the vast majority of cellular components. This approach has been used extensively to generate ECM scaffolds for regenerative medicine technologies and in 3D cell cul...
ORGANISM(S): Mus musculus (Mouse) 
2017-10-20 | PXD006428 | Pride
Proteomics Mass spectrometry Lc-srm Matrisome Tissue extraction Collagen Chemical digestion Extracellular matrix 
ProteomicsUnraveling the matrix: Proteomic profiling reveals stromal ECM dysregulation in severe early-onset fetal growth restriction
Severe, early-onset fetal growth restriction with absent or reversed end-diastolic umbilical artery velocities (FGRa/r) is marked by profound placental vascular insufficiency, yet the role of the villous stromal extracellular matrix (ECM) in this pathology remains poorly defined. Here, we applied an...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD070632 | Pride
Proteomics Fetal growth restriction Pregnancy Fibrosis Collagen Extracellular matrix Placenta 
ProteomicsExcess muscle plasma membrane leak disrupts extracellular matrix content and shifts macrophage-mediated muscle repair
Plasma membrane repair is critical for tissue integrity, especially for elongated contractile muscle cells. Genetically-mediated defects in plasma membrane resealing produce persistent leak, leading to a disordered extracellular matrix. Loss of the membrane repair protein dysferlin slows sarcolemma...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-15 | PXD077779 | Pride
Macrophage Muscle injury Dysferlin Duchenne muscular dystrophy Limb girdle muscular dystrophy Annexin Extracellular matrix 
ProteomicsECM-Focused Proteomic Analysis of Ear Punch Regeneration in Acomys cahirinus
In mammals, significant injury is generally followed by the formation of a fibrotic scar which provides structural integrity but fails to functionally restore damaged tissue. Spiny mice of the genus Acomys represent the first example of full skin autotomy in mammals. Acomys cahirinus h...
ORGANISM(S): Mus musculus (Mouse) Acomys cahirinus 
2025-10-31 | PXD047626 | Pride
Proteomics Regeneration Tandem mass spectrometry Wound healing Matrisome Scar-free Fibrosis Acomys cahirinus Spiny mouse Extracellular matrix 
ProteomicsHuman chromatin platforms for the study of transcription and RNA regulation
Here we describe tools to study the step-wise assembly of protein complexes on chromatin in a highly-controlled manner using reconstituted chromatin platforms and quantitative proteomic profiling. We profile the early steps in transcriptional activation and highlight the potential for understanding...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2018-05-15 | MSV000082363 | MassIVE
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