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ProteomicsMultiplexed quantitation of post-translational modified peptides in single cells using triggered MS/MS combined with super heavy tandem mass tags
Recent advances in mass spectrometry now allow unbiased proteome profiling of thousands of proteins from single cells using both label-free and labeling approaches. However, a major limitation of unbiased approaches is missing data, which worsens as the sample size increases. In addition, the reprod...
ORGANISM(S): Homo sapiens (Human) 
2026-03-13 | PXD073405 | Pride
Ptm Surequant Single cell proteomics Super heavy tandem mass tags 
ProteomicsQuantification of H3K27 methylation using heavy peptides as standards
To demonstrate the usability of our SIL peptides (JPT GmbH)on an MS application, 4 standard peptides were synthesized at 95% purity and each spiked at an amount 133 fmol into protein extracts of wild type HEK cells and EZH2-knockout cells, respectively. The spiked peptides in this experiment are his...
ORGANISM(S): Homo sapiens (Human) 
2020-04-23 | PXD018321 | Pride
Human Hek cells Histones modifications 
ProteomicsThe effect of interferons on presentation of defective ribosome products as HLA peptides
The class I major histocompatibility complex (MHC) bound peptides, produced from immature proteins that are degraded rapidly are called defective ribosome products (DRiPs). Such DRiPs are possibly involved with early alerting of the immune system about impeding infections, thus bringing about faster...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-25 | MSV000096209 | MassIVE
MetabolomicsEarly-life skin molecular signatures are predictive of atopic dermatitis risk in an Asian preconception birth cohort
Rationale: Early identification of infants at risk for atopic dermatitis (AD) is critical for timely prevention, yet robust preclinical biomarkers remain elusive. We characterized the longitudinal evolution of the skin microbiome, metabolome, and proteome to identify molecular signatures predictive ...
2026-10-05 | MTBLS14496 | MetaboLights
UnknownMitochondrial-derived peptides: Antidiabetic functions and evolutionary perspectives.
Not available
S-EPMC10838678 | biostudies-literature
ProteomicsPeptide standard acquired with the dual-gated SLIM-Orbitrap
Raw data collected on the dual-gated SLIM-Orbitrap. The sample contained a mixture of standard peptides at 1 uM equimolar concentration in 60:40 water:acetonitrile with 1% acetic acid (v/v). The peptides were kemptide, angiotensin I, bradykinin, neurotensin, angiotensin II, renin substrate tetradeca...
ORGANISM(S): Peptide Standards 
2023-08-23 | MSV000092738 | MassIVE
ProteomicsAn Internal Standard for Assessing Phosphopeptide Recovery from Metal Ion/Oxide Enrichment Strategies
Phosphorylation-mediated signaling pathways have major implications in cellular regulation and disease. Mass spectrometry-based proteomics is a well-established approach for quantifying thousands of phosphorylation events in a single experiment. However, proteins with roles in signaling pathways are...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2018-12-04 | PXD008966 | Pride
Tmt super-heavy Lumos Phosphorylation Mtraq Tmtzero Tmtsh Tmt0 
ProteomicsThe effect of interferons on presentation of defective ribosome products as HLA peptides
The class I major histocompatibility complex (MHC) bound peptides, produced from immature proteins that are degraded rapidly are called defective ribosome products (DRiPs). Such DRiPs are possibly involved with early alerting of the immune system about impeding infections, thus bringing about faster...
ORGANISM(S): Homo sapiens (Human) 
2021-06-09 | PXD022633 | Pride
Hla peptides Mhc Ifns Drips 
ProteomicsInference and quantification of peptidoforms in large sample cohorts by SWATH-MS: PTM-SWATH-MS Gold Standard data set
The PTM-SWATH MS Gold Standard data set consists of a previously published (Soste et al., 2014, PMID:25194849) set of 579 unpurified, synthetic, heavy-isotope labeled phosphopeptides (Thermo Scientific Biopolymers). These phosphopeptides represent biologically relevant sequences from S. cerevisiae p...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2017-06-12 | PXD004573 | Pride
Ipf Openswath Synthetic phosphopeptides Gold standard data set Human Yeast 
ProteomicsDevelopment of a parallel reaction monitoring (PRM) mass spectrometry-assay for the detection of SARS-CoV-2 spike glycoprotein and nucleoprotein
There is an urgent need for robust and high-throughput methods for SARS-CoV-2 detection in suspected pa-tient samples to facilitate disease management, surveillance, and control. Although nucleic acid detection methods such as RT-PCR are the gold standard, during the current pandemic the deployment ...
ORGANISM(S): SARS coronavirus WHU 
2022-01-12 | PXD021080 | Pride
Skyline Nucleoprotein Qexactive hf-x Parallel reaction monitoring Sars-cov-2 Heavy standard peptides Spike protein 
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