Sort   by:  
 Page size 
ProteomicsKinome profiling of diffuse large B-cell lymphoma cells in response to dasatinib
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease, with at least one-third of its patients not responding to the current chemotherapy regimen, R-CHOP. By gene expression profiling, patients with DLBCL can be categorized into two clinically relevant subtypes: activated B-cell (ABC) DL...
ORGANISM(S): Homo sapiens (Human) 
2018-12-14 | PXD009380 | Pride
Lymphoma Cancer Dasatinib Lc-ms Kinome 
ProteomicsLC-MS/MS of SETDB1 3TD after incubation with covalent ligands
In order to confirm which amino acid of the 3TD of SETDB1 is covalently modified by a set of cysteine-targeting ligands, we performed LC-MS/MS on sample containing 40 uM of SETDB1 3TD with 400 uM of ligand after overnight incubation at 4 C.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056206 | Pride
Setdb1 Unc9846 Unc10016 Unc10013 3td Unc10014 
ProteomicsImmunoprecipitation-Mass Spectrometry (IP-MS) identifies components of a Mce4A-containing complex
How lipids travel between membranes of diderm bacteria is a challenging mechanistic question because lipids, which are hydrophobic molecules, must traverse a hydrophilic periplasm. This question is even more complex for mycobacteria, which have a unique cell envelope that is highly impermeable to mo...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2022-02-16 | PXD023082 | Pride
Ip-ms Mycobacteria Ap-ms Mce transporters 
ProteomicsKinome profiling upon HCMV infection using the MIB-MS approach
Human cytomegalovirus (HCMV) is a significant cause of disease in immune-compromised adults and immune naïve newborns. No vaccine exists to prevent HCMV infection, and current antiviral therapies have toxic side effects that limit the duration and intensity of their use. There is thus an urgent need...
ORGANISM(S): Homo sapiens (Human) 
2017-03-20 | PXD005276 | Pride
Hcmv Human herpesvirus Kinase inhibitors Kinome Antivirals Virology Label-free quantitation 
ProteomicsProteomic analysis of antigen-capturing nanoparticles
Immunotherapy holds tremendous promise for improving cancer treatment. Administering radiotherapy with immunotherapy has been shown to improve immune responses and can elicit an “abscopal effect”. Unfortunately, response rates for this strategy remain low. Herein, we report an improved cancer immuno...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-26 | PXD006049 | Pride
Nanoparticles Cancer immunotherapy 
ProteomicsProteomic datasets from sacsin knockout human SH-SY5Y and mouse primary cortical neurons
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a childhood-onset cerebellar ataxia caused by mutations in SACS, which encodes the protein sacsin. Cellular ARSACS phenotypes include mitochondrial dysfunction, intermediate filament disorganization, and the progressive death of c...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-25 | PXD036906 | Pride
Neurobiology Arscacs Proteome Kinome Phosphoproteome Surfaceome 
ProteomicsIdentification of EGLN2 binding partners using AP-MS
Protein binding parnters of EGLN2 were identified in response to DMOG treatment.
ORGANISM(S): Homo sapiens (Human) 
2019-11-20 | PXD015787 | Pride
Proteomics Ap-ms 
TranscriptomicsTranscription profiling by array of yeast isolates at different time points during fermentation
Transcriptome analysis in natural Saccharomyces cerevisiae as function of fermentation stage. Strains used were the reference strain S288C, two (06L3FF02 and 06L6FF20) isolates from the Bairrada wine region, Portugal, three (Lalvin EC-1118, Lalvin ICV D254 and AEB Fermol Rouge) wine yeast obtained c...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-MTAB-112 | biostudies-arrayexpress
TranscriptomicsComparison of adult intact naive C57Bl/6 Nogo-A KO versus WT spinal cord
Nogo-A localized on myelin adaxonal membrane in the adult CNS is well known for its role as neurite outgrowth inhibitor following a lesion. Nogo-A KO mice show enhanced regenerative/compensatory fiber growth following CNS lesion. However, changes undergoing in their intact CNS have not been studied....
ORGANISM(S): Mus musculus 
2010-11-01 | E-GEOD-11276 | biostudies-arrayexpress
TranscriptomicsYap5-mediated transcriptional response to iron
Transcriptional response of S. cerevisiae to iron excess and Yap5 targets under high iron growth conditions.
ORGANISM(S): Saccharomyces cerevisiae 
2012-01-30 | E-MEXP-3193 | biostudies-arrayexpress
Sort   by:  
 Page size