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ProteomicsTemperature induced change of the HLA ligandome
Temperature induced change of the HLA ligandome and proteome in B-cells
ORGANISM(S): Homo sapiens (Human) 
2021-05-07 | PXD022930 | Pride
Hla class ii ligandome Hla class i ligandome Immunopeptidome Proteome Lc-ms/ms 
ProteomicsSampling from proteome to HLA-DR ligandome
Comprehensive analysis of the complex nature of the Human Leukocyte Antigen (HLA) class II ligandome is of utmost importance to understand the basis for CD4+ T cell mediated immunity and tolerance. Here, we implemented important improvements in the analysis of the repertoire of HLA-DR-presented pept...
ORGANISM(S): Homo sapiens (Human) 
2016-01-25 | PXD002951 | Pride
Ethcd Hcd Ligandome Hla class ii Etd Mhc class ii 
ProteomicsSampling from proteome to HLA-DR ligandome
Comprehensive analysis of the complex nature of the Human Leukocyte Antigen (HLA) class II ligandome is of utmost importance to understand the basis for CD4+ T cell mediated immunity and tolerance. Here, we implemented important improvements in the analysis of the repertoire of HLA-DR-presented pept...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-24 | MSV000082848 | MassIVE
ProteomicsHLA class II ligandome of colon cancer tissues for neoantigen identification
MS data of HLA class II ligandome of human colon cancer tissues
ORGANISM(S): Homo Sapiens (human) 
2024-09-25 | PXD054060 | JPOST Repository
ProteomicsMapping the HLA ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation
Immunopeptidome analysis of colorectal adenocarcinoma tissues as well as adjacent benign tissues was performed to characterize the natural HLA class I and class II presented ligandome represented in the context of malignancy as well as in benign tissue of the colon.
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD009602 | Pride
Neoplasia Cancer Hla-ligandomics Hla Colorectal adenocarcinoma Colon cancer Peptide Hla-restricted peptide Hla-ligand Colon 
ProteomicsThe HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy
Anti-leukemia immunity plays an important role for disease control and maintenance of tyrosine kinase inhibitor (TKI)-free remission in chronic myeloid leukemia (CML). Antigen-specific immunotherapy holds promise to strengthen immune control in CML, but requires the identification of CML-associated ...
ORGANISM(S): Homo sapiens (Human) 
2018-12-11 | PXD010450 | Pride
Mass spectrometry Chronic myeloid leukemia Immunopeptidome 
ProteomicsHLA class II ligandome from HOM-2 and JY cell lines (HLA-DR an HLA-DP ligands)
A high-throughput mass spectrometry analysis was used to identify more than 16,000 cell peptides bound to several HLA-DR and -DP class II molecules isolated from large amounts of two human cell lines (HOM-2 and JY).
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD028006 | Pride
Hla-dr Hla-dp 
ProteomicsHLA-I and HLA-II peptidomes for NESSIE
MS data of HLA class I and HLA class II ligandome of human colon tissue and LCLs
ORGANISM(S): Homo Sapiens (human) 
2024-08-08 | PXD047303 | JPOST Repository
ProteomicsHLA class I ligandome of colon cancer tissues for neoantigen identification
MS data of HLA class I ligandome of human colon cancer tissues
ORGANISM(S): Homo Sapiens (human) 
2021-07-26 | PXD026573 | JPOST Repository
ProteomicsTuning DO:DM ratios modulates HLA class II immunopeptidomes
Major Histocompatibility Complex Class II antigen presentation underlies a wide range of immune responses in health and disease. Although peptide ligand binding affinity has been the major focus for explaining and predicting class II antigens, we know that the levels and activities of accessory mol...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD024392 | Pride
Hla-ii Mhc Dm Antigen presentation Do Orbitrap 
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