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ProteomicsGAGfinder: glycosaminoglycan MS/MS fragment peak finding and elemental composition assignment
This study shows the efficacy of a new tandem mass spectrometry peak finding software, GAGfinder. GAGfinder works by iterating through all potential fragments of a given precursor composition and comparing a theoretical isotopic distribution to the peak heights found in a tandem mass spectrum. We us...
ORGANISM(S): Homo sapiens (Human) 
2018-04-09 | PXD009101 | Pride
Glycosaminoglycans Chondroitin sulfate Heparan sulfate Bioinformatics Keratan sulfate 
ProteomicsIntegrative glycomic and proteomic analysis of mouse striatum and lateral hypothalamus following cocaine and methamphetamine treatment
Drug abuse is a major concern with few therapeutic options. Heparan sulfate (HS) and chondroitin sulfate (CS) interact with a plethora of growth factors and their receptors, and have profound effects on cellular signaling. Thus, targeting these dynamic interactions represents a novel therapeutic mod...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-04 | PXD038576 | Pride
Chondroitin sulfate Mass-spectrometry Lateral hypothalamus Striatum Glycomics Drug abuse Methamphetamine Cocaine Proteomics Addiction Glycosaminoglycans Heparan sulfate Neurobiology Proteoglycans 
ProteomicsGlycomic and Proteomic changes in aging brain nigrostriatal pathway
This study identifies the age related changes in glycan receptors of heparan sulfate (HS) proteoglycan (receptor for rAAV2), and/or N-glycans with terminal galactose (receptor for rAAV9) and proteomics for receptors and co-receptors of adeno-associated virus in the nigro-striatal region of the brain...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-06-27 | PXD008990 | Pride
Hilic Mass spectrometry Reverse phase Gene therapy Aging nigro-striatal pathway Hilic-wax Lc-msms Label-free proteomics Heparan sulfate Adeno-associated virus N-glycans Proteomic Parkinson’s disease Glycomic 
UnknownCharacterization of COVID-19 disease in pediatric oncology patients: The New York-New Jersey regional experience.
Not available
S-EPMC7883045 | biostudies-literature
UnknownDUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGS.
Not available
S-EPMC6218860 | biostudies-literature
UnknownCommunity-based intervention to increase HIV testing and case detection in people aged 16-32 years in Tanzania, Zimbabwe, and Thailand (NIMH Project Accept, HPTN 043): a randomised study.
Not available
S-EPMC3156626 | biostudies-literature
UnknownAge-Related Differences in Socio-demographic and Behavioral Determinants of HIV Testing and Counseling in HPTN 043/NIMH Project Accept.
Not available
S-EPMC5718984 | biostudies-literature
UnknownEffect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a cluster-randomised trial.
Not available
S-EPMC4131207 | biostudies-literature
UnknownEffect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: results from the Look AHEAD randomized trial.
Not available
S-EPMC3410035 | biostudies-literature
UnknownEvaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention.
Not available
S-EPMC4077939 | biostudies-literature
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