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TranscriptomicsComparative Transcriptomics of Soybean Near Isogenic Lines in Response to Phytophthora Sojae
Phytophthora root and stem rot (PRR) of soybean, caused by Phytophthora sojae, is effectively controlled by Rps genes in soybean. Rps genes are race-specific, yet the mechanism of resistance, as well as susceptibility, remains largely unclear. Taking advantage of RNA-seq technology, we sequenced the...
ORGANISM(S): Glycine max 
2014-04-16 | E-GEOD-48524 | biostudies-arrayexpress
ProteomicsLFQ proteomics analysis of M. smegmatis treated with BacPROTACs.
To monitor selective degradation of ClpC1 and ClpC2 using BacPROTAC compounds in M. smegmatis we performed a LFQ proteomics analysis treating the cells at bactericidal compound concentration. We detected degradation of both proteins and additional dysregulation of the mycobacterial PQC system.
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2023-06-07 | PXD037235 | Pride
Antibiotics Tpd Bacprotac Protac Protein degradation 
UnknownNanoporous Membranes of Densely Packed Carbon Nanotubes Formed by Lipid-Mediated Self-Assembly.
Not available
S-EPMC10880049 | biostudies-literature
ProteomicsHigh-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficult to identify in current clinical practice. As a result, biology driven risk stratification and therapy assignment for medulloblastoma constitutes a major challenge...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD051235 | Pride
Proteomics Medulloblastoma Myc Immunohistochemistry 
ProteomicsHigh-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficult to identify in current clinical practice. As a result, biology driven risk stratification and therapy assignment for medulloblastoma constitutes a major challenge...
ORGANISM(S): Homo sapiens (Human) 
2025-03-06 | PXD051319 | Pride
Medulloblastoma Dia Proteomics Myc Immunohistochemistry 
UnknownSmall molecule inhibitors of mammalian glycosylation.
Not available
S-EPMC9713294 | biostudies-literature
TranscriptomicsSmall RNA mediated immune responses: insights from analyses of nine soybean R-gene near-isogenic lines and their susceptible parent
Small RNAs, including microRNAs (miRNAs) and small interfering RNAs (siRNAs) are negative regulators to target endogenous genes and repetitive sequences in plants. Although miRNAs and trans-acting or phased siRNAs (tasiRNAs or phasiRNAs) were found to target hundreds of disease related genes in Medi...
ORGANISM(S): Glycine max 
2015-04-15 | E-GEOD-56859 | biostudies-arrayexpress
ProteomicsSystematic Discovery of Deeply conse4rved Plant Protein Complexes, soy
The associated files are mass spec data from 2 Size exclusion chromatography experiments. The material was a native extract prepared from the green leafy tissue of approximately two-week-old soy sprouts. For size calibration the extract for the second fractionation was spiked with three size marke...
ORGANISM(S): Glycine max 
2019-10-28 | PXD013198 | Pride
Glycine max Size exclusion Cf-ms Soy 
UnknownmTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Not available
S-EPMC8356906 | biostudies-literature
ProteomicsA quantitative proteomics approach to monitor targeted protein degradation in M. smegmatis
Targeted protein degradation via the ubiquitin proteasome has been established in eukaryotes, however no application has been shown in bacteria so far. In the present work, selective protein degradation is shown using hetero bifunctional drugs, bringing substrates in close proximity to the bacterial...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Bacteria 
2022-08-12 | PXD021505 | Pride
Mycobacteria Targeted protein degradation Protease Tpd 
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